Page 8 - 04- Celiac Disease

5. Snyder J, Butzner JD, DeFelice AR, et al. Evidence-informed expert recommendations for the
management of celiac disease in children. Pediatrics. 2016;138(3):pii: e20153147.

ADDITIONAL READING

DeGeorge KC, Frye JW, Stein KM. et al. Celiac disease and gluten sensitivity. Prim Care.
2017;44(4):693–707.
Lebwohl B, Sanders DS, Green PHR. Coeliac disease. Lancet. 2019;391(10115):70–81.
Pinto-Sánchez MI, Verdu EF, Liu E, et al. Gluten introduction to infant feeding and risk of
celiac disease: systematic review and meta-analysis. J Pediatr. 2016;168:132.e3–143.e3.
Vaquero L, Rodríguez-Martín L, León F, et al. New coeliac disease treatment and their
complications. Gastroenterol Hepatol. 2018;41(3):191–204.

SEE ALSO

Algorithms: Diarrhea, Chronic; Malabsorption Syndrome

CODES

ICD10
K90.0 Celiac disease

CLINICAL PEARLS

Screen for celiac disease in patients with nonspecific GI symptoms, presumed IBS, dermatitis
herpetiformis, unexplained transaminitis, or unexplained iron deficiency anemia.
Test total IgA levels along with IgA anti-tTG antibodies in patients >2 years of age. Positive
serology is not definitive.
Diagnostic testing must be completed while on a gluten-containing diet.
Endoscopic biopsy with histologic examination of the intestinal mucosa is the gold standard
for diagnosis.
Standard of treatment is a gluten-free diet. Patient symptoms should improve in 7 days if fully
compliant.