Page 111 - MNU microbiology theoritical 2025
P. 111
General Microbiology & Immunology (PM 401) Second level Semester 4 2024/2025
C. Antimicrobial substances
1. Interferons
2.Antimicrobial peptide
3. Iron binding proteins
4. The complement system
1. Interferons
- It is a glycoprotein with a molecular weight of 28,000- 45,000 daltons.
- It acts nonspecifically to inhibit the spread of viral infections
- -IFN and -IFN: Produced by virus infected cells.
- They induce uninfected cells to produce antiviral proteins (AVPs) that inhibit
viral replication.
- -IFN: Produced by lymphocytes. It causes neutrophils and macrophages to
phagocytes bacteria. Also, involved in tumor immunology.
2.Antimicrobial peptide
They are cationic molecules released by neutrophils, monocytes and macrophages
Ex: defensins
General Microbiology & Immunology (PM 401) theoretical handbook Page 100
