Page 148 - MNU microbiology theoritical 2025
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     General Microbiology & Immunology (PM 401)         Second level                Semester 4                    2024/2025
               c) Protects mucous membranes by neutralizing viruses and toxins, immobilizing
                  motile organisms and preventing attachment of microbes to cell surfaces.
               .
                 4- IgD
               1. Structure - IgD exists only as a monomer.
               2. Properties :
               a) IgD is found in low levels in serum, its role in serum uncertain.
               b)  It is involved with the development and maturation of the antibody
               response5.
                 5- IgE
               1. Structure - IgE exists as a monomer
               2. Properties
               a) IgE is the least common serum Ig.
               b) Found bound via the Fc region to basophils and mast cells, rather than
               being free in circulation
               c) IgE also plays a role
                 ➢  allergic reactions because of its binding to basophils and mast cells.
                 ➢  Fighting  parasitic  helminth  diseases  as  eosinophils  bind  to  IgE-coated
                     helminths results in killing of the parasite.
                  General Microbiology & Immunology (PM 401)   theoretical handbook            Page 137





