Page 151 - The Miraculous Machine that Works for an Entire Lifetime: Enzyme

Adnan Oktar

places. This is revealed in a verse:

Allah, there is no deity but Him, the Living, the Self-Sustaining. He is
not subject to drowsiness or sleep. Everything in the heavens and the
earth belongs to Him. Who can intercede with Him except by His per-
mission? He knows what is before them and what is behind them, but
they cannot grasp any of His knowledge save what He wills. His
Footstool encompasses the heavens and the earth and their preserva-
tion does not tire Him. He is the Most High, the Magnificent. (Surat al-
Baqara: 255)

Enzyme Inhibitors
Enzymes are constantly active within the body. As a result of com-
munication between organelles, these proteins know when they must

go into action and operate non-stop. Sometimes, however, their activi-
ties must be halted or prevented. When the reactions in progress reach
a sufficient level to meet the cell's requirements—in other words, when
the intervention performed by enzymes is completed—the body has a
system to bring all their activities to an end. This really magnificent
control system is carried out by other proteins known as enzyme in-
hibitors.
Inhibitors inactivate an enzyme by binding to it. The binding of an
inhibitor is either reversible or irreversible. Irreversible inhibitors bind
covalently and change the enzyme chemically. Reversible inhibitors,
however, bind to enzymes non-covalently. There are two types of re-

versible inhibitors: competitive and non-competitive inhibitors.
A competitive inhibitor blocks the active site of an enzyme. The in-
hibitor is similar in structure to the real substrate and the enzyme binds
to the inhibitor rather than to its intended substrate. The enzyme's ac-
tive site is thus closed off in such a way as to prevent its binding to the
substrate at the same time.
A non-competitive inhibitor binds to a different site on an enzyme,

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