Page 10 - PC 101 Interactive practical book
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MANSOURA NATIONAL UNIVERSIY
PHARM D- CLINICAL PHARMACY LEVEL I PHARM. ANAL. CHEM. I (PC 101)
Standard Solutions:
It is a solution of known concentration & composition.
Types of standard solutions:
1. Primary Standard Solution:
♦ It is a solution whose concentration remains constant for a long
period of time.
♦ It is prepared directly by dissolving known weight of the primary
standard substance in a certain volume of solvent.
♦ Example: Na 2CO 3.
2. Secondary Standard Solution:
♦ It is a solution whose concentration can only be known approximately.
♦ The exact concentration of it is determined by a process called
"Standardization or Standardisation".
♦ Standardization must be done after the preparation of secondary
standard solutions to determine their exact concentration and
correct any error if present. That is done by:- Titrating the
secondary standard solution against a primary standard solution OR
against a previously standardized secondary standard.
♦ Examples: NaOH and HCl.
Remember: Solute + Solvent = Solution
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