Page 78 - Javanan Magazine Issue #1884
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PSYCHOLOGICAL
                             PSYCHOLOGICAL                                                                                             ISSUE No. 1882
                                                                                                                                        ISSUE No. 1856
                                PERSPECTIVES                                                                                            JAVANAN
                               PERSPECTIVES
                                                                                                                                        JAVANAN
                               Dr. Alan A.
                              Modarressi                            LOGICAL PERSPECTIVES
                                Clinical and               A SOCIOCULTURAL AND MIND AND BODY OUTLOOK
                             Neuro-Psychologyst
                                                           In this column, we examine the mental health issues in the context
                                                         of social, culture, and physiological concerns of the Iranian community
                                 THE PROCESS OF AGING AND FRAGILITY

                                                 How Older Adults Become Fragile with Aging


                  n a recent study undertaken by   have less Q10 enzyme in their blood   health of the blood vessels, prevents   that the coenzyme connects with to
                  several universities and research   plasma.” These levels, he continues,   damage due to vascular problems   lower the risk of a heart attack.
               Icenters in Spain and published   could be a reference for determining   that can be associated with the for-  A trial at the University of Colo-
               in journal Science &  Tech looked   how vulnerable people are and es-  mation of blood clots, and that can   rado Boulder, published by the
               into the molecular basis of human   tablishing therapies to palliate this.  also increase physical capacity  by   American Heart  Association, tried
               fragility in old ages.  They posed   The main deficiency in this mol-  improving the delivery of nutrients   a 20-milligram-a-day supplement
               the question why human beings be-  ecule is caused among people who   to the muscles.
               come fragile after the age of 65. The   cannot create it, mainly due to ge-  The association of physical ac-  with Q10 in the over-60s. The result
               study shows how a deficiency of   netic reasons. But the secondary one   tivity in elderly people with high   brought benefits to the endothelium
               coenzyme Q10, which charges our   can be a cause or consequence of   CoQ10  levels  could  not  only  im-  and a rise in blood flow.
               biological batteries, reduces mobil-  chronic conditions, such as diabetes   prove endothelial capacity [the lin-  Another relevant finding of the
               ity and the capacity for the genera-  or neurodegenerative illnesses.  ing of the blood vessels], but also   study is that women have greater
               tion of this vital molecule.       The researcher points to the fact                                 deficits of CoQ10 than men.  This
                 The Q10 coenzyme is vital. If cel-  that a lower presence of this fun-  reduce the release of vesicles and   result needs to be studied more.
               lular mitochondria are the body’s   damental  lipid  creates  a  spiral  of   factors involved in inflammation   They believe it could be related to
               batteries, this lipid (Fat) is their char-  decline that has to be reversed. Lev-  and the senescence phenotype ag-  the evolution of the muscles after
               ger, being responsible for the trans-  els of  Q10  fall  with lower levels   ing.                   menopause, but that it is a field that
               port of electrons and also serving   of physical activity, and the lower   What’s  more,  the  results  of  the
               as a key antioxidant for the proper   these levels, the lower the capacity   research indicate that high levels of   requires more exploration, as well as
               working of the body. A deficiency of   to exercise. It’s a vicious circle and   CoQ10 are directly linked with low-  the effects on cognitive capacity in
               Q10, which is linked to aging, gen-  a dramatic one, because functional-  er cardiovascular risk due to their re-  general. This will be the subject of
               erates an energy insufficiency that is   ity is lost as well as the ability to get   lationship with cholesterol, particles   his next project.
               related to mitochondrial conditions,   it back.
               cardiac diseases, strokes and neu-  To break  this  trend, there are  a
               rodegenerative pathologies, such   number of complementary strate-
               as Alzheimer’s disease and Parkin-  gies. The first is to increase physical
               son’s. A new study has, for the first   activity in a regular and progressive
               time, associated low levels  of this   way. The second is to correct this
               coenzyme with sarcopenia, the de-  deficit via diet. The Mediterranean
               generative loss of skeletal muscle   diet and, in particular, the consump-
               mass, which creates fragility in old-  tion of nuts and varied vegetables
               er people. The study reveals that this   with vegetable oils. From there, the
               is more common in women.          direction of the spiral can be invert-
                 The Q10 coenzyme is a key piece   ed: the correction of the deficiency
               in the biological puzzle, in particu-  allows for more exercise to be done
               lar for the brain, heart and muscles   and this helps to increase the levels
               – precisely the organs that need the   of the coenzyme in the blood.
               most energy and are the most vul-  There are also specific supple-
               nerable to such a deficit. A study   ments on the market, but the re-
               published by the team from the An-  searcher warns that  these must
               dalusian Centre of Developmental   always be taken under medical su-
               Biology (CABD) in the publication   pervision. “There is no need to take
               Antioxidants has revealed that this   them every day nor in large quanti-
               is also a cause and a consequence   ties. They can also be counterpro-
               of fragility in people aged over 65,   ductive when combined with other
               as well as being a factor related to   pharmaceuticals.
               cardiovascular risk.               With these preventions, the ben-
                 The authors of the study sum it   efits of a rise in the presence of the
               up: “Older people who have more   Q10 enzyme are evident. The rise
               symptoms  or markers  of fragility   in the plasma levels improves the

                        DANESH FOROUGHI, PH.D.                                           Alan Modarressi, PhD, QME
                        Licensed Clinical Psychologist, PSY13680                                Licensed Clinical Psychologist
                Licensed Marriage, Family & Child Psychotherapist, MFC23455                       Qualified Medical Evaluator
                    Certified National Board of Addiction Examiners #4974                       Certified Psychophsychologist
                              Tel: (310) 940-3642                                   Diplomat, American Academy of Pain Management
                   15720 Ventura Blvd., Second Fl. #224 Encino CA 91436             (818) 501-6080            (562) 861-7226

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