Page 14 - NTM Insight Pamphlet 2024

TREATMENTS & SIDE EFFECTS*
Class
Medication Names (Brand Names)
Form
Notes
Common Side Effects
Rifamycin^
Rifampin (Rifadin®, Rimactane®)
Rifabutin (Mycobutin®)
Capsule
Capsule
Generally used to treat MAC, along with ethambutol plus macrolide.
Rifamycins may permanently stain contact lenses orange. Consider disposable contact lenses.
Can interact with other drugs, especially anti-fungal medications and newer CF drugs.
Red, brown or orange saliva, sweat, tears or feces; diarrhea/upset stomach; fever, chills, flu-like symptoms; flushing; itching; rash; elevated liver enzymes; blood count abnormality
(Myambutol®)
Pill
Patients on ethambutol should have regular vision checks.
Macrolide
Clarithromycin (Biaxin®)
Azithromycin (Zithromax®)
Pill Pill
Do not take a macrolide alone (monotherapy) or in combination with a quinolone as the only companion drug for the macrolide to treat MAC. This combination is associated with the emergence of macrolide resistance.
Patients on azithromycin should have an EKG and regular hearing checks.
Irregular heart rhythm; hearing changes; nausea; muscle weakness; kidney problems; metallic taste; diarrhea; abdominal pain; rash
Ethambutol
Vision changes; numbness, tingling in hands and feet; rash
INSIGHT - A Patient’s Perspective
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