Page 64 - P4403.14_V85_YOUROTC_Book OCTOBER_2023[Digital]29_09
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64  HEALTHCARE                                                                                                                                                                                    HEALTHCARE  65



                                                                                                                                                   The only OTC erectile

                                                                                                                                                   dysfunction treatment that

                                                                                                                                                                                                         *, 1
                                                                                                                                                   is effective up to            .
                                 RAPID RELIEF                                                                                                           Only works with sexual stimulation




                                 FROM TOOTHACHE                                                                                                         Tadalafil is supported by 20 years of real-world clinical
                                                                                                                                                        experience as prescription only-medicine
                                                                                                                                                                                                   2
                                 AND MOUTH ULCERS                                                                                                       Starts working from 30 minutes after administration
                                                                                                                                                        Absorption not affected by food


                                                                              UK’S
                                                                                                                                      Save
                                                                          •      TOOTHACHE BRAND*     •
                                                                                                                                    11%
                                                                                                                                    AVAILABLE
                                                                                                                                               Off
                                                                                                                                        NOW
                                                                                                                                     Trade











                                                                                                                                Cialis® Together is indicated in adult men with erectile dysfunction,
                                                                                                                                which is the inability to achieve or maintain a penile erection
                                                                                                                                sufficient for satisfactory sexual activity.  Product           Size  Case   Buying   RRP  Trade    POR   Pip Code
                                                                                                                                                                                                    Size  Price/Single   Offer %  %
                                                                                                                                For Cialis® Together to be effective, sexual stimulation is required.
                                                                                                                                                                              CIALIS
                                                                                                                                                                               Cialis Together 10mg Tabs  4  1  £11.41  £21.99  11%  38% 423-7467
                                                                                                                                OTC, over-the-counter. ED, erectile dysfunction.
                                                                                                                                References: 1. Viagra Connect®. Summary of Product Characteristics. 2022.     Cialis Together 10mg Tabs  8  1  £19.71  £37.99  11%  38% 423-7475
                                                                                                                                2. Sanofi Data on File. Prepared 10.02.2023.
                                                                                                                                 Cialis Together 10mg tablets Product Information   to vasodilators including patients with left ventricular outflow obstructions  the  incidence  of  adverse  reactions.  CYP3A4  inducers  such  as  rifampicin,
                                                                                                                                                                  (e.g. aortic stenosis) or multiple atrophy should consult their doctor before  phenobarbital,  phenytoin  and  carbamazepine  may  decrease  plasma
                                                                                                                                 Presentation: Cialis  Together  10mg  film-coated  tablets  containing  10mg
                                                                                                                                                                  taking  Cialis  Together.  Patients  should  check  with  their  doctors  before  concentrations of tadalafil and decrease efficacy.
                                                                                                                                 of tadalafil.
                                                                                                                                                                  taking  Cialis  Together  with  doxazosin  and  other  alpha  blockers.  In  case
                                                                                                                                                                                                   Pregnancy and breastfeeding: Cialis Together is not indicated for use in
                                                                                                                                 Indications:  Erectile dysfunction in adult men. In order for Cialis Together  of  sudden  visual  defect  or  sudden  decrease  or  loss  of  hearing  patient
                                                                                                                                 to  be  effective,  sexual  stimulation  is  required. Dose and administration:   should  stop  Cialis  Together  and  seek  medical  attention  immediately.   women. Adverse Reactions: Adverse events observed from spontaneous
                                                                                                                                                                                                   reporting and clinical trials: Common (≥1/100 and<1/10): Headache, flushing,
                                                                                                                                 Men 18 years of age or over: The recommended dose is one 10mg tablet  Patients  with  severe  renal  impairment  and  severe  hepatic  impairment   nasal  congestion,  dyspepsia,  back  pain,  myalgia,  pain  in  extremity.
                                                                                                                                 taken at least 30 minutes prior to anticipated sexual activity. The maximum  should  consult  their  doctor  before  taking  Cialis  Together.  Patients  who   Uncommon  (≥1/1,000  and  <1/100):  Hypersensitivity  reactions,  dizziness,
                                 *CIRCANA UNIT SALES | MAT TY VS YA | TOTAL COVERAGE | 10.06.2023.                               dosing  frequency  is  once  per  day.  Cialis  Together  is  not  recommended  experience  erections  lasting  4  hours  or  more  should  seek  immediate   blurred  vision,  eye  pain,  tinnitus,  tachycardia,  palpitations,  hypotension,
                               FOR VERIFICATION PLEASE EMAIL UKENQUIRIES@CHURCHDWIGHT.COM.                                       for continuous daily use. Contraindications: Hypersensitivity to the active  medical assistance. Patients who have conditions which may predispose   hypertension,  dyspnoea,  epistaxis,  abdominal  pain,  vomiting,  nausea,
                                                                                                                                 substance or to any of the excipients, co-administration with nitric oxide  them  to  priapism  (such  as  sickle  cell  anaemia,  multiple  myeloma
                                                                                                                                                                                                   gastro-oesophageal  reflux,  rash,  haematuria,  prolonged  erections,  chest
                   ORAJEL®DENTAL GEL, ORAJEL EXTRA STRENGTH AND ORAJEL MOUTH GEL CONTAINS BENZOCAINE.                            donors  or  nitrates,  cardiac  disease  in  patients  where  sexual  activity  is  or  leukaemia),  should  consult  a  doctor  before  taking  Cialis  Together.   pain, peripheral oedema, fatigue.  Rare (≥1/10,000 and <1/1000): Angioedema,
                                                                                                                                 inadvisable, myocardial infarction within the last 90 days, unstable angina  Cialis Together should not be used in a patient who has an anatomical
                                                                                                                                                                                                   stroke  (including  haemorrhagic  events),  syncope,  transient  ischaemic
                          ALWAYS READ THE LABEL. Orajel Sensitivity ProSHIELD Toothpaste is a cosmetic product.                  or angina during sexual intercourse,  NYHA class 2 or greater heart failure  deformation of the penis. Patients taking potent CYP3A4 inhibitors should   attacks, migraine, seizures, transient amnesia, visual field defect, swelling
                                                                                                                                 in the last 6 months, uncontrolled arrhythmia, hypotension (< 90/50 mm  consult  a  doctor  before  taking  Cialis  Together.  Patients  should  avoid
                                                                                                                                 Hg),  uncontrolled  hypertension,  stroke  within  6  months,  non-arteritic  drinking excessive amounts of grapefruit juice. The use of Cialis Together   of eyelids, conjunctival hyperaemia, non-arteritic anterior ischemic optic
                                                                                                                                                                                                   neuropathy,  retinal  vascular  occlusion,  sudden  hearing  loss,  myocardial
                                                                                                                                 anterior  ischaemic  optic  neuropathy  causing  loss  of  vision  in  one  eye,  with  other  treatments  for  erectile  dysfunction  is  not  recommended.
                                                                                                                                                                                                   infarction,  unstable  angina  pectoris,  ventricular  arrhythmia,  urticaria,
                                                                                                                                 co-administration  with  guanylate  cyclase  simulators  (e.g.  riociguat),  Patients should not drink large amounts of alcohol before sexual activity.
                                                                                                                                                                                                   Stevens-Johnson syndrome, exfoliative dermatitis, hyperhydrosis, priapism,
                                                                                                                                 deformation  of  the  penis  (such  as  angulation,  cavernosal  fibrosis  or  Use  of  Cialis  Together  with  recreational  drugs  (including  but  not  limited   penile  haemorrhage,  haematospermia,  facial  oedema,  sudden  cardiac
                                                                                                                                 Peyronie’s disease), women, those without erectile dysfunction and men  to “poppers”, nitrous oxide, GHB/GBL, methamphetamines, MDMA/ecstasy,
                                                                                                                                 under 18 years of age.  Warnings and precautions: All men with erectile  ketamine,  flunitrazepam,  cannabis,  opioids,  cocaine,  etc.)    may  lead  to   death.  RRP (ex VAT):  8  tablets  pack:  £31.66,  4  tablets  pack:  £18.33.  Legal
                                                                                                                                 dysfunction  should  be  advised  to  consult  their  doctor  within  6  months  adverse  events  such  as  dizziness,  decrease  of  blood  pressure,  stroke  or   category:  P.   Product Licence: Cialis  Together  has  a  GB  licence;  Licence
                                                                                                                                                                                                   number:  PLGB  53886/0074.  Product  licence  holder:  Sanofi,  410  Thames
                                                                                                                                 for  a  clinical  review  of  potential  underlying  conditions  and  risk  factors  heart attack, seizures, priapism, and coma. Cialis Together contains lactose;
                                                                                                                                                                                                   Valley  Park  Drive,  Reading,  Berkshire,  RG6  1PT,  UK.   Further information is
                                                                                                                                 associated with erectile dysfunction.  If symptoms of erectile dysfunction  Patients with rare hereditary problems of galactose intolerance, the Lapp
                                                                                                                                                                                                   available from Sanofi, 410 Thames Valley Park Drive, Reading, Berkshire,
                                                                                                                                 have  not  improved  after  taking  Cialis  Together  on  several  consecutive  lactase  deficiency  or  glucose-galactose  malabsorption  should  not   RG6 1PT.
                                                                                                                                 occasions or if their erectile dysfunction worsens patients should consult  take Cialis Together. Effects on ability to drive and use machines: Cialis
                                                                                                                                 their doctor. Patients who have undergone pelvic surgery or radical non  Together has negligible influence on the ability to drive or use machines.  Email: uk-medicalinformation@sanofi.com
                                                                                                                                 nerve sparing prostatectomy or with known hereditary degenerative retinal  Although the frequency of reports of dizziness in placebo and tadalafil arms
                                                                                                                                                                                                   Document number:  MAT-XU-2301953 v1.0
                                                                                                                                 disorders  (e.g  retinitis  pigmentosa)  should  consult  their  doctor  before  in clinical trials was similar, patients should be aware of how they react
                                                                                                                                 taking  Cialis  Together.  Patients  with  cardiovascular  disease  should  be  to Cialis Together, before driving or using machines. Interactions: Patients   Date of preparation: May 2023.
                                                                                                                                 advised that sexual activity carries a cardiac risk and if they experience  should  not  take  Cialis  Together  with  nitrate  medicines  (glyceryl  trinitrate,
                                                                                                                                 chest pain during sexual activity they should refrain from any further sexual  isosorbide mononitrate, isosorbide dinitrate), nitric oxide donors (such as
                                                                                                                                 activity  and  seek  medical  attention  immediately.  Cialis  Together  is  not  amyl nitrite (“poppers”), nicorandil, molsidomine or sodium nitroprusside),   Adverse events should be reported. Reporting forms and
                                                                                                                                 recommended for patients who experience chest pain or breathlessness  riociguat  or  other  guanylate  cyclase  stimulators.    Patient  should  consult   information can be found at www.mhra.gov.uk/yellowcard.
                                                                                                                                 after light or moderate activity. Patients should consult their doctor before  their  pharmacist  or  doctor  before  taking  Cialis  Together  with  doxazosin
                                                                                                                                                                                                    Adverse events should also be reported to the Sanofi drug
                                                                                                                                 resuming sexual activity if they have: uncontrolled hypertension, moderate  and  other  alpha  1  adrenergic  blockers,  5-alpha  reductase  inhibitors  (e.g.   safety department on 0800 0902522
                                                                                                                                 to  severe  valvular  disease,  left  ventricular  dysfunction,  hypertrophic  finasteride),  antihypertensives,  other  treatments  for  erectile  dysfunction,
                                                                                                                                 obstructive  and  other  cardiomyopathies,  significant  arrhythmias,  had  theophylline,  ethinylestradiol  or  terbutaline.  CYP3A4  inhibitors  such  as
                                                                                                                                 coronary artery bypass surgery or angioplasty, asymptomatic controlled  ketoconazole,  itraconazole,  erythromycin,  clarithromycin,  cimetidine,  and
                                                                                                                                                                                                                       MAT-XU-2301288  May 2023
                                                                                                                                 hypertension, mild valvular disease. Patient with an increased susceptibility  grapefruit juice should be administered with caution as they may increase
                                                          Case   Buying    POR
                                     Product         Size  Size  Price/Single   RRP  %  Pip Code                                Cialis Trade Advert A4 Portrait v5.indd   1                                                23/05/2023   13:41
                                                                                                                                 ONLINE HCP TRAINING
                                                                                                                                                                                                                           23/05/2023   13:41
                                                                                                                                Cialis Trade Advert A4 Portrait v5.indd   1
                                     ORALJEL
                                           DENTAL JEL  5.3G  12  £2.50  £4.29  30%  276-0239                                     Please scan the QR code to access a 10 minute online training module.
                                           MOUTH GEL  5.3G  12  £2.50  £4.29  30%  276-0270                                      This is targeted towards pharmacists and the pharmacy team to
                                       EXTRA STRENGTH  5.3G  12  £3.42  £5.84  30%  276-0247
                                                                                                                                 explain how they can advise men on the appropriate use of Cialis
                                                                                                                                 Together (tadalafil 10mg).
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