Page 36 - P4304.1-V115 PS Magazine November 2025
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What this means


              •  Sub-£1 Cat M items barely contribute: ~10p profit per item after clawback, even with
                 a 25% discount off DT price

              •  The ≥£1 Cat M items perform better (~67p per item), but the sizeable 20.7% share under
                 £1 drags the overall Cat M average down to ~56p per item.

              •  Because Cat M dominates dispensing volume, this low return from a fifth of lines dilutes
                 overall profitability, making reliance on Cat C discounts essential to keep the practice
                 in the black.
              Now let’s look at the top prescribed generics in 2024/25. The table below illustrates what I am
              trying to get over. I have even added in a 50% generic discount off DT price

               Drug                      Tariff Entry                Cat      DT Price  Net              Net
                                                                              (£)          Margin        Margin
                                                                                           (25%          (50%
                                                                                           Disc) (£)     Disc) (£)
               Atorvastatin              Atorvastatin 20mg tablets   M        0.62         0.09          0.24

               Amlodipine                Amlodipine 5mg tablets      M        0.59         0.08          0.23

               Lansoprazole              Lansoprazole 15mg gastro-   M        0.76         0.11          0.30
                                         resistant capsules
               Omeprazole                Omeprazole 20mg gastro-     M        0.81         0.11          0.31
                                         resistant capsules
               Ramipril                  Ramipril 10mg capsules      M        1.23         0.17          0.48

               Levothyroxine sodium      Levothyroxine sodium        M        0.61         0.08          0.24
                                         50microgram tablets
               Bisoprolol fumarate       Bisoprolol 5mg tablets      M        0.86         0.12          0.33
               Colecalciferol            Colecalciferol              A        6.20         0.86          2.41
                                         800unit tablets
               Metformin hydrochloride   Metformin 500mg tablets     M        0.58         0.08          0.23
               Sertraline hydrochloride  Sertraline 100mg tablets    M        0.99         0.14          0.38


              •  At 25% discount, Cat M items make pennies per prescription which is regardless of how
                  good a generic price you buy at.
              •  At 50% discount, margins roughly triple, but still remain under £0.50 per item for most
                  Cat M drugs.
              •  Colecalciferol (Cat A) stands out, generating £2.41 profit per item at 50% discount and
                  of course this is where your opportunity lies as there are many discounted brands available
                  so you need to do your research.
              What I am getting at here, is that whilst you need and want to make margin on your fastest
              moving lines they really generate very little income on reimbursement and if it weren’t for the
              dispensing fee then you would not be able to afford to dispense them.

              You must focus on Cat C and brands as Cat C manufacturer discounts are the most viable
              route to protect margin.












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         P4304.1-V115 PS Magazine November 2025.indd   36                                                        13/10/2025   14:07:15
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