Page 19 - P4403.59-V61_Numark Pharmacy Magazine Mar 25 PRINT 2_Neat

2 mg/5 ml

(400 mcg/ml) Are you making the
strength
The first non-branded 2 mg/5 ml most of your Numark

glycopyrronium bromide oral solution Brand Support deals?

An opportunity for adolescents to continue their treatment into adulthood

For the symptomatic treatment of severe sialorrhoea (chronic If you maximised your Brand Support
pathological drooling) due to chronic neurological disorders of usage, you could potentially receive up to
childhood-onset in patients aged 3 years and older. £403 in rebates per month*.
1
Check out the Membership Dashboard
Colonis Glycopyrronium Bromide 2 mg/5 ml Oral Solution to see how you can maximise your Brand
gives patients the opportunity to continue their stable dose Support rebate… It pays to be with Numark!
into adulthood. 1

• The 2 mg/5 ml solution is available in 60 ml and 250 ml bottles.

• Sugar-free, strawberry flavour – strawberry is the most popular

flavour with children. 2
• A formulation suited for children with swallowing issues. 3

• Licensed for use with nasogastric and/or PEG tubes. 1

PIP Codes: 128-0841 (60 ml), 128-0833 (250 ml)

Colonis Glycopyrronium Bromide Oral Solution 2 mg/5 ml is now
available to order via Phoenix

PRESCRIBING INFORMATION inhaled anaesthetics. May delay absorption of other medication. Concurrent use with slow-
Please consult the Summary of Product Characteristics (SmPC) before prescribing. dissolving tablets of digoxin, atenolol or metformin may result in increased serum levels of these
medicines. Use with parasympathomimetics may antagonise the effect.
Product name: Glycopyrronium Bromide 2 mg/5 ml Oral Solution Adverse effects:
Composition: Each 5 ml contains 2 mg of glycopyrronium bromide Serious: Allergic reaction, seizure (worsening), transient bradycardia, angle-closure glaucoma,
Indications: Symptomatic treatment of severe sialorrhoea (chronic pathological drooling) due to urinary retention (common), pneumonia (common), pyrexia (common), behavioural
chronic neurological disorders of childhood-onset in patients aged 3 years and older. changes (very common) £67 a month can be earned on these 5 products
Dosage and administration: Dosing is based on the weight of the child. Using the graduated Very common: Dry mouth, constipation, diarrhoea, vomiting, flushing, nasal congestion, reduced
syringe provided, initiate dosing at 0.02 mg/kg three times daily and titrate in increments of bronchial secretions. Consult the SmPC for further details and for other adverse reactions. alone based on average pharmacy usage**.
0.02 mg/kg every 5-7 days. Adjust dose to achieve optimal symptomatic control with minimal NHS price: 60 ml: £76.80, 250 ml: £320
adverse effects. The maximum recommended dosage is 0.1 mg/kg three times daily not
exceeding 1.5-3 mg per dose based on weight. Refer to dosing table (Table 1) in Summary of Legal category: Prescription Only Medicine
Product Characteristics. Dose should be given one hour before or two hours after meals. For oral Marketing Authorisation Holder: Colonis Pharma Limited, 25 Bedford Square, Bloomsbury, Average Your potential monthly rebate
use and use via nasogastric & PEG feeding tubes. London, WC1B 3HH, United Kingdom Pipcode Supplier Brand Support Product Pack pharmacy Net
Contraindications: Hypersensitivity to glycopyrronium bromide or excipients; angle-closure MA number: PL 41344/0071 Size usage price Small Medium Large
glaucoma; myasthenia gravis; pyloric stenosis; paralytic ileus; prostatic enlargement; urinary Job number: GB-CPL-066-001
2
retention; severe renal impairment (eGFR < 30 ml/min/1.73 m , including those with end-stage
renal disease requiring dialysis); intestinal obstruction; pregnancy & breastfeeding; potassium Date of preparation: December 2024 3175510 Napp BUTRANS PATCHES 10MCG/HR 4 1.4 £11.50 £21.48 £34.37 £49.41
chloride solid oral dose products; other anticholinergic drugs. Contraindicated during pregnancy
and whilst breastfeeding. Adverse events should be reported. Reporting forms and information can be found DURAPHAT 5000 FLUORIDE
Warnings and precautions: Not recommended in children under 3 years and should not be used at: https://yellowcard.mhra.gov.uk/ or search for MHRA Yellow Card in the Google Play or 3207776 Colgate TPASTE POM 51G 51g 24 £5.47 £6.30 £10.08 £14.50
in children with mild to moderate sialorrhoea or in patients over 65 years. Use with caution in Apple App Store. Adverse events should also be reported to Colonis Pharma Limited via
children with compromised blood brain barrier. Reduced dose should be considered for patients Clinigen E-mail: drugsafety@clinigengroup.com
with renal failure. Use with caution in gastro-oesophageal reflux disease, ulcerative colitis, Fax number: +44 (0) 1932 824284 3778081 Dr Falk URSOFALK TABS 500MG 100 0.3 £47.40 £5.37 £8.59 £12.35
pre-existing constipation, acute myocardial infarction, hypertension, conditions characterised
by tachycardia (including hyperthyroidism, cardiac insufficiency, cardiac surgery), coronary
artery disease, cardiac arrhythmias, patients receiving inhalation anaesthesia. Diarrhoea may Abbreviation 3225687 Abbvie GANFORT EYE DROPS 3ml 2.3 £8.00 £9.55 £15.29 £21.97
be an early symptom of incomplete intestinal obstruction, especially in patients with ileostomy PEG, percutaneous endoscopic gastronomy.
or colostomy, and treatment with this drug would be inappropriate and possibly harmful. As BBI
glycopyrronium bromide inhibits sweating, patients with increased temperature should be References 2429793 Healthcare GLUCOGEL 3 pack 31 £5.95 £8.38 £13.41 £19.28
observed closely. In high environmental temperature, heat prostration can occur. Avoid repeated 1. Colonis Pharma Ltd. Glycopyrronium Bromide 2 mg/5 ml Oral Solution Summary of Product
or large doses in patients with uraemia. Patients with fructose intolerance should not take this Characteristics. Available from: https://www.medicines.org.uk/emc/.
medicine due to presence of sorbitol. The product contains sodium propyl parahydroxybenzoate 2. Generation R. What flavour would children choose for their medicines? Available from: https://
(E217) and sodium methyl parahydroxybenzoate (E219) which may cause allergic reactions generationr.org.uk/what-flavour-would-children-choose-for-their-medicines/
(possibly delayed). Treatment should be evaluated in the event of constipation, overheating, [Accessed January 2025].
urinary retention, pneumonia, allergic reaction, pyrexia, very hot weather, changes in behaviour. 3. Batchelor HK and Mariott JF. Formulations for children; problems and solutions. Br J Pharmacol.
Safety data beyond 24 weeks are not available. Treatment should be kept as short as possible. 2015;79(3):405–418. * Calculated using PCA data from NHSBSA – based on pharmacy dispensing 6,500 scripts.
May produce drowsiness or blurred vision, thus patients should not operate machinery. © Colonis Pharma Limited 2025
Drug interactions: Combinations with drugs with antimuscarinic effects (e.g. amantadine, ** Potential monthly rebate subject to change each month due to additions/deletions/price changes and prescribing data.
tricyclic antidepressants, antihistamines, clozapine; disopyramide; MAOIs, nefopam; memantine, Registered in England & Wales No. 05486832. For more information please view our Privacy
phenothiazines) may add to adverse effects and can also lead to confusion in the elderly. Use Policy. VAT Registration No. 862418028. Registered office: Colonis Pharma Ltd, 25 Bedford Square,
with corticosteroids may result in increased intraocular pressure. There are specific interactions Bloomsbury, London, WC1B 3HH.
with domperidone, metoclopramide, levodopa, haloperidol; nitrates; topiramate, zonisamide; January 2025 | GB-CPL-066-002
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P4403.59-V61_Numark Pharmacy Magazine Mar 25.indd 19 07/02/2025 11:51:01