Page 29 - Pharmaceutical_Analytical_Chemistry_1_Theoretical_Notes_Level_1 2024-2025
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     Mansoura National University
            Pharm D-Clinical Pharmacy Program                 Level 1             Pharm. Anal. Chem. 1 (PC 101)
                                                    Mole Concept
                   •  Molecules and atoms are extremely small objects - both in size and mass.
                   •  The mole is a standard scientific unit for measuring quantities of very small
                       entities such as atoms or molecules.
                   •  1 Mole           6.022 × 10 23
                       AVOGADRO’S NUMBER
                       (Atoms/Molecules/…  )
                                                             23
                   •  3 Moles                  3 × 6.022 × 10
                   •  It is also equal to the formula weight (atomic or molecular) of a substance
                       expressed in grams.
               Note:
                   •  weight = mass
                   •  for atoms: it is termed atomic weight or atomic
                       mass
                   •  for molecules: it is termed molecular weight or
                        molecular mass
                   •  Notice that: Na, K, are atoms, H2O, N2, H2SO4
                       are molecules.
                   ▪  Formula or molecular weight: The sum of the atomic weights of the atoms
                       that make up a compound.
                   •  e.g. MW of NaOH = 23 + 16 + 1 = 40 g
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