Page 54 - Genomic Medicine in Emerging Economies
P. 54

Conclusions and Outlook    43




           However, integrating TCM with modern medicine at the omics level in order
           to contribute to more targeted personalized medicine is a long and arduous
           process that requires the accumulation and synthesis of knowledge in many
           fields, including  genomics/genetics,  molecular  biology,  pharmacology,  epi-
           demiologic studies on gene-disease associations, gene-environment-behavior
           interactions, and genomics-informed clinical trials of TCM health interven-
           tions. Advances in omics may also provide new opportunities for TCM in
           public health that focus on disease prevention, because genomic studies can
           provide genetic information at the individual level as well as at the population
           level, thus increasing the interaction and the interdependence between the tra-
           ditional healthcare delivery system, which focuses on treatment of individuals,
           and the public health system, which focuses on prevention, suboptimal health
           management, and control in populations (Wang et al., 2014). Notably, this
           enhanced interaction is creating a shared population health information focus
           on using genomic advances appropriately and effectively to promote health
           and to prevent disease, which can be applied to TCM its prevention aspect.
           Ultimately, with increasing integration, the modern form of TCM will continue
           to progress in the postgenomics era for a more integrated, evidence-based, and
           personalized health care. Hence TCM has the potential to be a new and rap-
           idly emerging driver for novel molecular-targeted personalized medicine in the
           coming decade.



           CONCLUSIONS AND OUTLOOK

           China has a large population spread over a large land mass; in addition, China
           suffers from imbalanced economic development. Although China has invested
           in  the  basic  research  of  genome  science,  it  is  urgent  for  China  to  develop
           public health genomic programs and clinical genetic services that meet the
           needs of the Chinese people, particularly residents in rural areas. A standard
           framework for evaluating genetic/genomic testing and related interventions in
           China is also needed. What is more, the Chinese government should imple-
           ment genomic education into the Chinese health care system. China needs an
           easy way for the public to obtain genetic information on innovation, educa-
           tion, and prevention. The understanding of TCM has advanced greatly along
           with data-intensive genomics and omics biotechnologies. However, integrating
           TCM with modern medicine at the omics level in order to contribute to a more
           targeted personalized medicine is a long and arduous process that requires
           accumulation and synthesis of knowledge in many fields. Advances in omics
           will provide new opportunities for TCM in public health that focus on dis-
           ease prevention, because genomic studies can provide genetic information at
           individual level as well as in the population as a whole, thus increasing the
           interaction and the interdependence between the traditional healthcare deliv-
           ery system, which focuses on treatment of individuals, and the public health
   49   50   51   52   53   54   55   56   57   58   59