Page 38 - ASOP CASTING MANUAL June 25

4.1

Inflammation

Introduction Inflammation is a fundamental biological response to tissue injury ,
infection or other harmful stimuli The classic symptoms of inflammation were

first described by the Roman medical writer Aulus Cornelius Celsus in the
century AD, and they remain critical diagnostic tools in modern healthcare
These signs are essential for understanding mechanisms inflammation and
guiding effective patient care In this lecture we will discuss the five cardinal

signs of inflammation and their physiological significance with references to
historical

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