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1st Int. Transborder Conf. of the Timor Island: Timor %u2013 Science without borderDili, 7-8 May 2025121Coronary Intervention In A Patient With Angina PectorisSergio H. G. FernandesUniversidade Nacional Timor Lorosa%u2019e, Timor-LesteAbstractThe cardiovascular system has as its primary function the provision of blood circulation to the various organs of the human body, including the heart itself. The disease of the coronary arteries, which, through various mechanisms, results in a reduction (either absolute or relative) in coronary blood flow, is known as ischemic heart disease, and it is the leading cause of death globally. According to official data from the World Health Organization, 17.9 million people die annually from cardiovascular diseases, with more than half of these deaths occurring in Asia, showing a rapid increase from 5.6 million in 1990 to 10.8 million deaths in 2019. The majority of deaths from cardiovascular diseases are due to ischemic heart disease. By 2020, deaths from coronary diseases in TimorLeste accounted for 11.5% (814 recorded cases), and the age-adjusted mortality rate was 126.6 per 100,000 inhabitants. This data placed Timor-Leste in the 69th position worldwide. Ischemic heart disease is a condition of the coronary arteries that, through various mechanisms, leads to a reduction (either absolute or relative) in coronary blood flow, and is the leading cause of death worldwide. Stable angina pectoris is the most prevalent form of ischemic heart disease that, from a clinical point of view, is characterized by precordial pain with characteristic radiation, triggered by exercise or emotions, and relieved by rest or nitroglycerin. This study case shows the effectiveness of treatment Stable Angina Pectoris with special emphasis on invasive coronary angiography and angioplasty as methods of diagnosis and treatment of the disease. The case of a patient with angina pectoris was presented, who, despite medical treatment, continued to be symptomatic. The most striking finding in the examination and noninvasive tests was severe mitral insufficiency. However, invasive coronary angiography revealed multivessel disease with severe obstructive lesions, which, when treated with a drug-eluting stent, not only improved the patient's symptoms but also the severity of the mitral insufficiency. This demonstrated the usefulness of coronary angioplasty in controlling symptoms and complications in patients with stable angina. Finally, a real clinical case of a patient with angina pectoris was presented and discussed, in which coronary angioplasty associated with medical treatment was able to improve the patient's sign and symptoms and reduce the severity of severe mitral insufficiency. Keywords: Angina pectoris; Ischemic heart disease; Invasive coronary angiography; Coronary angioplasty.