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                                      LIST OF FIGURES






        Figure 1 Compliance, persistence, adherence   8
        Figure 2:  General perception on the opening of the bottle  11
        Figure 3:  General perception on the handling of the bottle  11
         Figure 4: Mean IOP at morning trough   51
         Figure 5: Comparison of mean IOP at the three month time points  61
        Figure 6: Fluctuations in ocular perfusion pressure compared to base-line at 1-, 6-, and 12 months visits with DTFC and LTFC
        treatment  124
         Figure 7: IOP during 24 hours   71
        Figure 8: 24 hours after injection of BAK DTFC   163
        Figure 9: 24 hours after injection of PF DTFC   163
         Figure 10: Evaluation of corneal endothelium toxic damages   164
        Figure 11:  Patients’ and ophthalmologists’ satisfaction   193
        Figure 12: GSS change   206
         Figure 13: 24h IOP levels  215



                                       LIST OF TABLES




        Table 1 - Study summary 6
        Table 2 - Study claims   7
        Table 3: IOP mesurements     81
        Table 4: Mesurements of CRA RI, OA RI, SPCA RI  123
        Table 5 Events with PF and PC dorzolamide/timolol   173
        Table 6: Improvement of local tolerability under monotherapy with PF DTFC 184






























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