Page 158 - Human Umbilical Cord Mesenchymal Stem Cells

The Wharton's Jelly Is an Ideal Source of Stem Cells

Fig 8. (A-C) Expression levels of adipogenic, osteogenic and chodrogenic genomic markers in
differentiated WJ, PV, SA, AM and MC cells. (A) The expression levels of the adipogenic-related genes
CEBPβ, FABP4, PPARγ and PREF1 were increased for WJ, PV, SA, AM and MC compared to their
respective controls with no significant differences between them. (B) The expression levels of the
osteogenic-related genes osteocalcin (OCN), osteopontin (OPN), alkaline phosphatase (ALP) and bone
sialoprotein (BSP) were significantly greater for WJ compared to PV, SA, AM and MC (*p<0.05). (C) The
expression levels of the chondrogenic-related genes collagen type II (COL2A1), cartilage oligomeric matrix

PLOS ONE | DOI:10.1371/journal.pone.0127992 June 10, 2015 17 / 25