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23. Biccard BM, Goga S, De Beurs J. Dexmedetomidine and cardiac protection for non-cardiac surgery: A meta-
analysis of randomised controlled trials. Anaesthesia. 2008;63(1):4-14. doi:10.1111/j.1365-2044.2007.05306.x
24. Kawazoe Y, Miyamoto K, Morimoto T, et al. Effect of dexmedetomidine on mortality and ventilator-free days in
patients requiring mechanical ventilation with sepsis a randomized clinical trial. JAMA - J Am Med Assoc.
2017;317(13):1321-1328. doi:10.1001/jama.2017.2088
25. Wang C, Datoo T, Zhao H, et al. Midazolam and dexmedetomidine affect neuroglioma and lung carcinoma cell
biology in vitro and in vivo. Anesthesiology. 2018;129(5):1000-1014. doi:10.1097/ALN.0000000000002401
26. Lavon H, Matzner P, Benbenishty A, et al. Dexmedetomidine promotes metastasis in rodent models of breast,
lung, and colon cancers. Br J Anaesth. 2018;120(1):188-196. doi:10.1016/j.bja.2017.11.004
27. Bruzzone A, Piñero CP, Castillo LF, et al. α2-Adrenoceptor action on cell proliferation and mammary tumour
growth in mice. Br J Pharmacol. 2008;155(4):494-504. doi:10.1038/BJP.2008.278
28. Xia M, Ji N, Duan M, et al. Dexmedetomidine regulate the malignancy of breast cancer cells by activating α2-
adrenoceptor/ERK signaling pathway. Eur Rev Med Pharmacol Sci. 2016;20:3500-3506.
29. Connolly JG, Tan KS, Mastrogiacomo B, et al. Intraoperative opioid exposure, tumour genomic alterations, and
survival differences in people with lung adenocarcinoma. Br J Anaesth. 2021;127(1):75-84.
doi:10.1016/j.bja.2021.03.030
30. Owusu-Agyemang P, Cata JP, Kapoor R, et al. An analysis of the survival impact of dexmedetomidine in children
undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Int J Hyperth. 2018;35(1):435-
440. doi:10.1080/02656736.2018.1506167
31. Cata J, Singh V, Lee B, et al. Intraoperative use of dexmedetomidine is associated with decreased overall survival
after lung cancer surgery. J Anaesthesiol Clin Pharmacol. 2017;33(3):317-323. doi:10.4103/joacp.JOACP_299_16
32. Ackerman RS, Luddy KA, Icard BE, Piñeiro Fernández J, Gatenby RA, Muncey AR. The Effects of Anesthetics
and Perioperative Medications on Immune Function: A Narrative Review. Anesth Analg. 2021;133(3):676-689.
doi:10.1213/ANE.0000000000005607

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