Page 5 - CASA Bulletin of Anesthesiology 2022; 9(2) (5)

Vol. 9, No 2, 2022

本期专栏

Intraoperative Management of Hypoxemia during One-lung Ventilation: What is New?

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Michael Guan , David Fanelli , Manxu Zhao , Henry Liu
1 Department of Anesthesiology & Perioperative Medicine
Milton S. Hershey Medical Center
Pennsylvania State University College of Medicine
Hershey, PA 17033
2 Department of Anesthesiology
Cedar Sinai Medical Center
8700 Beverly Boulevard

Los Angeles, CA 90048
3 Department of Anesthesiology & Critical Care
Perelman School of Medicine
University of Pennsylvania
3401 Spruce Street
Philadelphia, PA 19104

Correspondence to Dr. Henry Liu
Henry Liu, MD
Department of Anesthesiology & Critical Care
Perelman School of Medicine
University of Pennsylvania
3401 Spruce Street
Philadelphia, PA 19104
Email: henryliupa@gmail.com

Dr. Michael Guan Abstract
Hypoxemia during one-lung ventilation (OLV) occurs frequently.
It is a challenge all thoracic anesthesiologists will have to face and
deal with. A thorough understanding of the physiology of oxygen
delivery and tissue utilization is paramount in optimizing these
patients during OLV. Oxygen delivery is recently discovered to be
not correlated directly with peripheral oxygen saturation during
OLV. Though the traditional means such as increasing FiO2,
applying PEEP, adjusting I:E ratio, recruiting more alveoli to
participate in oxygenation, and minimizing shunt are still important,
the importance of hemoglobin concentration and cardiac output is
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