Page 367 - كتاب تمريض نسا الاكتروني

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2- Combined oral contraceptive (COC)

Mechanism of action:

• Suppression of ovulation (negative feedback on hypothalamus & pituitary)

• Thick cervical mucus (most important)

• Inhibit tubal motility

• Atrophic endometrium

• Inhibition of sperm capacitation

Advantages

• ASER "available, safe, effective (failure rate 1-2%), reversible"

• No special acts during sexual acts

• Extra contraceptive benefits

1. Decrease Bleeding, PID, Benign breast disease

2. Decrease cancer endometrium I ovary,

3. Decrease Dysmenorrhea

4. Decrease Ectopic pregnancy, treat endometriosis

Disadvantages

• Doesn’t prevent sexually transmitted disease

• Strokes

• Gall stones

• Diabetogenic

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