Page 385 - ترم ثاني كتاب تمريض صحة الام الكتروني
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               2-  Combined oral contraceptive (COC)


               Mechanism of action:



                   •  Suppression of ovulation (negative feedback on hypothalamus & pituitary)

                   •   Thick cervical mucus (most important)


                   •   Inhibit tubal motility


                   •  Atrophic endometrium


                   •  Inhibition of sperm capacitation



               Advantages


                   •  ASER "available, safe, effective (failure rate 1-2%), reversible"


                   •  No special acts during sexual acts


                   •  Extra contraceptive benefits


                   1.     Decrease Bleeding, PID, Benign breast disease


                   2.    Decrease cancer endometrium I ovary,

                   3.    Decrease Dysmenorrhea


                   4.     Decrease Ectopic pregnancy, treat endometriosis



               Disadvantages


                   •  Doesn’t prevent sexually transmitted disease


                   •  Strokes


                   •  Gall stones


                   •  Diabetogenic



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