Page 152 - Ebook-Book JCMS 2025

A Comparative Study of Cervicography and Histopathology
Report from a Colposcopic-directed Biopsy at Thammasat
University Hospital, 2023-2024
Pitchapong Kittiniyom, Kanokwan Promchit*, Komsun Suwannarurk, Dittakarn Boriboonhirunsarn
Department of obstretic and gynecology, Faculty of Medicine, Thammasat university
*Corresponding Author E-mail: tuthakanokwan@gmail.com
Objective: Methods: Abstract
To determine the efficacy of cervicography interpretation by medical personnel with various
experience levels.
This retrospective descriptive study was conducted at Thammasat University Hospital
between October 1, 2023, and November 30, 2024. Participant were women who had
indication for colposcopic directed biopsy (CDB). Cervical pictures with good quality
taken during CDB were reviewed independently by residency trainees, fellowship and
attending staff. Histopathological results from CDB were used as the reference standard.
Cervicography interpretation was compared to the histopathology results to assess
diagnostic agreement. Sensitivity, specificity, positive predictive value (PPV), and negative
predictive value (NPV) were calculated to assess the diagnostic performance of
cervicography interpretation
Results: A total of 160 participants were recruited. The mean age of subjects was 42.5 years old. One
third (59/160) of participants had high grades in cervical cytology. One quarter (40/160) of
subjects had cervical intraepithelial neoplasia 2 (CIN 2) or more. Sensitivity of attending
staff, fellowship and two residency trainees were 45, 47.5, 45 and 47.5% respectively.
Specificity of attending staff, fellowship and two residency trainees were 87.5, 95.5, 85.8
and 78.3% respectively. PPV of attending staff, fellowship and two residency trainees were
54.6, 76, 51.4 and 42.2% respectively, NPV of attending staff, fellowship and two residency
trainees were 82.7, 84.4, 82.4 and 81.7% respectively.
Conclusions: Sensitivity, specificity, PPV and NPV of cervicography to detect CIN2+ ranged from 45 to 48,
78 to 95, 42 to 76 and 81 to 84 percents, respectively.
150 Joint Conference in Medical Sciences 2025