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Amblyopia:
Choice of Therapy
The following therapies are used alone or in combination as required to achieve the
therapeutic goal.
Optical correction: The amblyopic eye must have the most accurate optical correction
possible. This should occur prior to any occlusion therapy because vision may improve
with spectacles alone. Full cycloplegic refraction should be given to patients with
accommodative esotropia and amblyopia. In other patients, a prescription less than the
full plus measurement that was refracted may be prescribed given that the decrease in
plus is symmetric between the two eyes. Because accommodative amplitude is believed
to be decreased in amblyopic eyes, one needs to be cautious about cutting back too
much on the amount of plus. Refractive correction alone has been shown to improve
amblyopia in up to 77% of patients.
Occlusion: Patching may be full-time or part-time. Standard teaching has been that
children need to be observed at intervals of 1 week per year of age, if undergoing full-
time occlusion to avoid occlusion amblyopia in the sound eye . In addition to adhesive
patches, opaque contact lenses, occluders mounted on spectacles, and adhesive tape
on glasses have been used
Penalization: Penalization therapy was reserved for children who would not wear a
patch or in whom compliance was an issue. The Amblyopia Treatment Studies,
however, have demonstrated that atropine penalization in patients with moderate
amblyopia (defined by the study as visual acuity better than 20/100) is as effective as
patching. The Amblyopia Treatment Studies were performed in children aged 3-7 year
Surgery to treat the cause of the amblyopia
In general, occlusive adhesive patches should be used during the initial therapy in many
cases of amblyopia; however, in mild to moderate amblyopia, penalization with atropine
drops has been shown to be an effective alternative
Strabismus:
Ocular alignment should be established as soon as possible, especially in young children, to
maximize binocularity, prevent or facilitate treatment of amblyopia, and normalize
appearance. In almost all cases, clinically important refractive errors should be corrected.
Amblyopia treatment is usually started before surgery, because this may reduce the angle
of strabismus or increase the likelihood of good postoperative binocularity.
The following treatment modalities are used alone or in combination as required to achieve
the therapeutic goal:
Correction of refractive errors
Bifocals
Miotics
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