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. Spring-Loaded Model Revisited: Paramyxovirus Fusion Requires Engagement of a Receptor Binding . New Enzyme-Activated Solubility-Switchable Contrast Agent for Magnetic Resonance Imaging: From
Protein beyond Initial Triggering of the Fusion Protein. Matteo Porotto, Ilaria DeVito, Samantha G. Synthesis to in Vivo Imaging. Beata Jastrzabska, Rejean Lebel, Helene Therriault, J. Oliver McIntyre,
Palmer, Eric M. Jurgens, Jia L. Yee, Christine C. Yokoyama, Antonello Pessi and Anne Moscona. J. Virol. Emanuel Escher, Briggitte Guerin, Benoit Paquette, Witold A. Neugebauer, and Martin Lepage. Journal of
2011, 85 (24) pp 12867-12880. DOI: 10.1128/JVI.05873-11. Medicinal Chemistry. 2009, 52 (6) pp 1576–1581. February 19, 2009. DOI: 10.1021/jm801411h.
. Toward the Optimization of Bombesin-Based Radiotracers for Tumor Targeting. Ibai E. Valverde, Sandra . Design of a Heterotetravalent Synthetic Allergen That Reflects Epitope Heterogeneity and IgE Antibody
Vomstein, and Thomas L. Mindt. Journal of Medicinal Chemistry. 2016, April 7, 2016. DOI: Variability to Study Mast Cell Degranulation. Michael W. Handlogten, Tanyel Kiziltepe and Basar Bilgicer.
10.1021/acs.jmedchem.6b00025. Biochem. J. 2013, 449 (1) pp 91–99. January 1, 2013. DOI: 10.1042/BJ20121088.
. 2-Mercaptoacetylglycylglycyl (MAG2) as a Bifunctional Chelator for 99mTc-Labeling of Cyclic RGD Dimers: . A Non-Chromatographic Method for the Purification of a Bivalently Active Monoclonal IgG Antibody from
Effect of Technetium Chelate on Tumor Uptake and Pharmacokinetics. Jiyun Shi, Young-Seung Kim, Biological Fluids. Basar Bilgicer, Samuel W. Thomas III, Bryan F. Shaw, George K. Kaufman, Vijay M.
Sudipta Chakraborty, Bing Jia, Fan Wang and Shuang Liu. Bioconjugate Chemistry. 2009, 20(8) pp Krishnamurthy, Lara A. Estroff, Jerry Yang, and George M. Whitesides. Journal of the American Chemical
1559–1568. July 15, 2009. DOI: 10.1021/bc9001739. Society. 2009, 131 (26) pp 9361–9367. June 17, 2009. DOI: 10.1021/ja9023836.
. Optical Imaging of Integrin αv β3 Expression with Near-Infrared Fluorescent RGD Dimer with . Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2
Tetra(ethylene glycol) Linkers. Zhaofei Liu, Shuanglong Liu, Gang Niu, Fan Wang, Shuang Liu, Xiaoyuan activity In vivo in a mouse model. Rejean Lebel, Beata Jastrzebska, Helene Therriault, Marie-Michele
Chen. Mol Imaging. 2010, 9 (1) pp 21-29. February 1, 2010. DOI: Cournoyer, J. Oliver McIntyre, Emanuel Escher, Witold Neugebauer, Benoit Paquette, and Martin
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629979/. Lepage. Magnetic Resonance in Medicine. 2008, 60 (5) pp 1056–1065. October 27, 2008. DOI:
10.1002/mrm.21741.
. 99mTc-Galacto-RGD2: A Novel 99mTc-Labeled Cyclic RGD Peptide Dimer Useful for Tumor Imaging.
Shundong Ji, Andrzej Czerwinski, Yang Zhou, Guoqiang Shao, Francisco Valenzuela, Paweł Sowiński, . Design of a Heterobivalent Inhibitor of Allergy and More Physiologically Relevant Allergy Models. Michael
Satendra Chauhan, Michael Pennington, and Shuang Liu. Mol. Pharmaceutics. 2013, 10 (9) pp 3304–3314. William Handlogten. University of Notre Dame. 2013, March 28, 2013.
July 22, 2013. DOI: 10.1021/mp400085d.
. Evaluation of the Pharmacokinetic Effects of Various Linking Group Using the 111In-DOTA-X-
. Novel Synthetic Route to Peptide-Capped Gold Nanoparticles. Takeshi Serizawa, Yu Hirai, and Mamoru BBN(7−14)NH2 Structural Paradigm in a Prostate Cancer Model. Jered C. Garrison, Tammy L. Rold, Gary L.
Aizawa. Langmuir. 2009, 25 (20), pp 12229–12234. September 21, 2009. DOI: 10.1021/la9021799. Sieckman, Farah Naz, Samantha V. Sublett, Said Daibes Figueroa, Wynn A. Volkert and Timothy J.
Hoffman. Bioconjugate Chem. 2008, 19 (9) pp 1803–1812. August 20, 2008. DOI: 10.1021/bc8001375.
. In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug
candidate. Jlenia Brunetti, Chiara Falciani, Giulia Roscia, Simona Pollini, Stefano Bindi, Silvia Scali, Unai . Positron Emission Tomographic Imaging of Copper 64– and Gallium 68–Labeled Chelator Conjugates of
Cossio Arrieta, Vanessa Gomez-Vallejo, Leila Quercini, Elisa Lbba, Marco Prato, Gian Maria Rossolini, Jordi the Somatostatin Agonist Tyr3-Octreotate. Jessie R. Nedrow, Alexander G. White, Jalpa Modi, Kim
Llop, Luisa Bracci, and Alessandro Pini. Scientific Reports. 2016, 6 (26077). May 12, 2016. DOI: Nguyen, Albert J. Chang and Carolyn J. Anderson. Molecular Imaging. 2014, 13 pp 1-13. Decebmer 14,
10.1038/srep26077. 2014. DOI: 10.2310/7290.2014.00020.
. Controlling HBV Replication in Vivo by Intravenous Administration of Triggered PEGylated siRNA- . PEG-Peptide Conjugates. Ian W Hamley. Biomacromolecules. 2014. April 1, 2014. DOI:
Nanoparticles. Sergio Carmona, Michael R. Jorgensen, Soumia Kolli, Carol Crowther, Felix H. Salazar, 10.1021/bm500246w.
Patricia L. Marion, Masato Fujino, Yukikazu Natori, Maya Thanou, Patrick Arbuthnot, and Andrew D.
Miller. Mol. Pharmaceutic., 2009, 6 (3), pp 706–717. January 21,2009. DOI: 10.1021/mp800157x. . A Systematic Analysis of Peptide Linker Length and Liposomal Polyethylene Glycol Coating on Cellular
Uptake of Peptide-Targeted Liposomes. Jared F. Stefanick, Jonathan D. Ashley, Tanyel Kiziltepe, and
. Evaluation of 99mTc-Labeled Cyclic RGD Peptide with a PEG4 Linker for Thrombosis Imaging: Comparison Basar Bilgicer. ACS Nano. 2013, 7 (4) pp 2935–2947. February 19, 2013. DOI: 10.1021/nn305663e.
with DMP444. Wei Fang, Jia He, Young-Seung Kim, Yang Zhou, and Shuang Liu. Bioconjugate Chem. 2011,
22 (8), pp 1715–1722. July 24, 2011. DOI: 10.1021/bc2003742. . Design and Synthesis of Multifunctional Gold Nanoparticles Bearing Tumor-Associated Glycopeptide
Antigens as Potential Cancer Vaccines. Raymond P. Brinãs, Andreas Sundgren, Padmini Sahoo, Susan
. Species Differences of Bombesin Analog Interactions with GRP-R Define the Choice of Animal Models in Morey, Kate Rittenhouse-Olson, Greg E. Wilding, Wei Deng, and Joseph J. Barchi, Jr. Bioconjugate Chem.
the Development of GRP-R-Targeting Drugs. Theodosia Maina, PhD; Berthold A. Nock, PhD; Hanwen 2012, 23 (8), pp 1513-1523. July 19, 2012. DOI: 10.1021/bc200606s.
Zhang, Anastasia Nikolopoulou, Msci, Beatrice Waser, PhD; Jean Claude Reubi, MD; and Helmut R.
Maecke, PhD. Journal of Nuclear Medicine. 2005, 46 (5) pp. 823-830. January 23, 2005. . Mechanistic Studies of a Peptidic GRP78 Ligand for Cancer Cell-Specific Drug Delivery. Ying Liu, Sebastian
C.J. Steiniger, YoungSoo Kim, Gunnar F. Kaufmann, Brunhilde Felding-Habermann, and Kim D. Janda.
. Trivalent PEGylated Platform for the Conjugation of Bioactive Compounds. Angela Torres, Carlos Mas- Molecular Pharmaceutics 2007 4(3) p 435-447. January 2007. DOI:10.1021/mp060122j.
Moruno, Enrique Perez-Paya, Fernando Albericio, and Miriam Royo. Bioconjugate Chem. 2011, 22 (10),
pp 2172–2178. August 25, 2011. DOI: 10.1021/bc100393g. . Membrane-Fusogen Distance Is Critical for Efficient Coiled-Coil-Peptide-Mediated Liposome Fusion.
Geert A. Daudey, Harshal R. Zope, Jens Voskuhl, Alexander Kros , and Aimee L. Boyle. Langmuir. 2017, 33
. Design and Evaluation of Novel Polymyxin Fluorescent Probes. Bo Yun , Kade D. Roberts, Philip E. (43) pp 12443-12452. 10/5/2017. DOI: 10.1021/acs.langmuir.7b02931.
Thompson, Roger L. Nation, Tony Velkov, and Jian Li. Sensors. 2017, 17 (11) pp 2598. 11/11/2017. DOI:
10.3390/s17112598. . Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and
Its Effect on ADC Efficacy. Magdalena Dorywalska, Pavel Strop, Jody A. Melton-Witt, Adela Hasa-Moreno,
. Evaluation of the Pharmacokinetic Effects of Various Linking Group Using the 111In-DOTA-X- Santiago E. Farias, Meritxell Galindo Casas, Kathy Delaria, Victor Lui, Kris Poulsen, Janette Sutton, Gary
BBN(7−14)NH2 Structural Paradigm in a Prostate Cancer Model. Jered C. Garrison, Tammy L. Rold, Gary L. Bolton, Dahui Zhou, Ludivine Moine, Russell Dushin, Thomas-Jaume Pons, Arvind Rajpal. Plos One. 2015,
Sieckman, Farah Naz, Samantha V. Sublett, Said Daibes Figueroa, Wynn A. Volkert and Timothy J. 10 (7) e0132282. July 10, 2015. DOI: 10.1371/journal.pone.0132282.
Hoffman. Bioconjugate Chem. 2008, 19 (9) pp 1803–1812. August 20, 2008. DOI: 10.1021/bc8001375.
. Peripheral administration of a long-acting peptide OT receptor agonist inhibits fear induced freezing.
. Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site. Meera E. Modi, Mark J. Majchrzak, Kari R. Fonseca, Angela Doran, Sarah Osgood, Michelle Vanase-
Nathan J. Alves, Matthew M. Champion, Jared F. Stefanick, Michael W. Handlogten, Demetri T. Frawley, Eric Feyfant, Heather McInnes, Ramin Darvari, Derek L. Buhl, and Natasha M. Kablaoui. JPET.
Moustakas, Yunhua Shi, Bryan F. Shawd, Rudolph M. Navari, Tanyel Kiziltepe, Basar Bilgicer. Biomaterials. 2016, 357 (3). May 23, 2016. DOI: 10.1124/jpet.116.232702.
2013, 34 (22) pp 5700–5710. April 16, 2013. DOI:.org/10.1016/j.biomaterials.2013.03.082.
. Novel Monodisperse PEGtide Dendrons: Design, Fabrication, and Evaluation of Mannose Receptor-
. Membrane-Fusogen Distance Is Critical for Efficient Coiled-Coil-Peptide-Mediated Liposome Fusion. Mediated Macrophage Targeting. Jieming Gao, Peiming Chen, Yashveer Singh, Xiaoping Zhang, Zoltan
Geert A. Daudey, Harshal R. Zope, Jens Voskuhl, Alexander Kros , and Aimee L. Boyle. Langmuir. 2017, 33 Szekely, Stanley Stein, and Patrick J. Sinko. Bioconjugate Chem. 2013, 24 (8) pp 1332–1344. June 29,
(43) pp 12443-12452. 10/5/2017. DOI: 10.1021/acs.langmuir.7b02931. 2013. DOI: 10.1021/bc400011v.
. Design, Synthesis and Evaluation of a Neurokinin 1 Receptor-Targeted Near IR Dye for Fluorescence . B-Peptide Conjugates: Syntheses and CD and NMR Investigations of B/a-Chimeric Peptides, of a DPA-B-
Guided Surgery of Neuroendocrine Cancers. Ananda Kumar Kanduluru, Madduri Srinivasarao, and Philip Decapeptide, and of a PEGylated b-Heptapeptide. James Gardiner, Raveendra I. Mathad, Berhard Jaun,
S. Low. Bioconjugate Chemistry. 2016, pp 1-20. August 16, 2016. DOI: 10.1021/acs.bioconjchem.6b00374. Jurg V. Schreiber, Oliver Flogel, and Dieter Seebach. Helvetica Chimica Acta. 2009, 92 (12) pp 2698-2721.
December 17, 2009. DOI: 10.1002/hlca.200900325.
. Tumor Uptake of the RGD Dimeric Probe 99mTc-G3-2P4-RGD2 is Correlated with Integrin rv_3 Expressed
on both Tumor Cells and Neovasculature. Zhaofei Liu, Bing Jia, Jiyun Shi, Xiaona Jin, Huiyun Zhao, Fang Li, . A Synthetic Virus-Like Particle Streptococcal Vaccine Candidate Using B-Cell Epitopes from the Proline-
Shuang Liu, and Fan Wang. Bioconjugate Chem. 2010, 21 (3) pp 548-555. February 25, 2010. DOI: Rich Region of Pneumococcal Surface Protein A. Marco Tamborrini, Nina Geib, Aniebrys Marrero-
10.1021/bc900547d. Nodarse, Maja Jud, Julia Hauser, Celestine Aho, Araceli Lamelas, Armando Zuniga, Gerd Pluschke, Arin
Ghasparian and John A. Robinson. Vaccines. 2015, 3 (4), pp 850-874, October 16, 2015. DOI:
. Polyproline-Rod Approach to Isolating Protein Targets of Bioactive Small Molecules: Isolation of a New 10.3390/vaccines3040850.
Target of Indomethacin. Shin-ichi Sato, Youngjoo Kwon, Shinji Kamisuki, Neeta Srivastava, Quian Mao,
Yoshinori Kawazoe, and Motonari Uesugi. Journal of the American Chemical Society. 2007, 129 (4), pp . Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular
873–880. January 4, 2007. DOI: 10.1021/ja0655643. degranulation. Peter E Deak, Maura R Vrabel, Vincenzo J Pizzuti, Tanyel Kiziltepe, and Basar Bilgicer.
Experimental Biology and Medicine. 2016, 0 pp 1-11. April 13, 2016. DOI: 10.1177/1535370216644533.
. Controlled liposome fusion mediated by SNARE protein mimics. Hana Robson Marsden, Alexander V.
Korobko,Tingting Zheng, Jens Voskuhla and Alexander Kros. Biomaterials Science. 2013, 1 (10) pp 1046- . Photocleavable peptide-oligonucleotide conjugates for protein kinase assays by MALDI-TOF MS.
1054. June 4, 2013. DOI: 10.1039/C3BM60040H. Guangchang Zhou, Faraz Khan, Qing Dai, Juliesta E Sylvester and Stephen J Kron. Molecular BioSystems.
2012, 8 (9), pp 2395-2404. June 13, 2012. DOI: 10.1039/C2MB25163A.
. SNARE protein analog-mediated membrane fusion. Pawan Kumar, Samit Guha and Ulf Diederichsen.
Journal of Peptide Science. 2015, April 7, 2015. DOI: 10.1002/psc.2773. . A Synthetic Trivalent Hapten that Aggregates anti-2,4-DNP IgG into Bicyclic Trimers. Başar Bilgiçer,
Demetri T. Moustakas, and George M. Whitesides. Journal of the American Chemical Society. 2007, 129
. In Situ Modification of Plain Liposomes with Lipidated Coiled Coil Forming Peptides Induces Membrane (12) pp 3722-3728. February 28, 2007. DOI: 10.1021/ja067159h.
Fusion. Frank Versluis , Jens Voskuhl , Bartjan van Kolck , Harshal Zope , Marien Bremmer , Tjerk
Albregtse and Alexander Kros. Journal of the American Chemical Society. 2013, 135 (21), pp 8057–8062. . Synthetic Allergen Design Reveals the Significance of Moderate Affinity Epitopes in Mast Cell
May 9, 2013. DOI: 10.1021/ja4031227. Degranulation. Michael W. Handlogten, Tanyel Kiziltepe, Nathan J. Alves, and Basar Bilgicer. ACS
Chemical Biology. 2012, 7 (11) pp 1796–1801. August 10, 2012. DOI: 10.1021/cb300193f.
. Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity
and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar . Multifunctional nanoparticles as simulants for a gravimetric Immunoassay. Scott A. Miller, Leslie A. Hiatt,
Bilgicer. ACS Nano. 2013, 7 (9) pp 8115–8127. August 29, 2013. DOI: 10.1021/nn4033954. Robert G. Keil, David W. Wright, and David E. Cliffel. Analytical and Bioanalytical Chemistry. 2011, 399 (3)
pp 1021-1029 January 1, 2011. DOI:10.1007/s00216-010-4419-8.
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