Page 149 - Binder2
P. 149

Benefit of
                    Durable                   Explanation
                   Biologics
                                 Without tolerization, there's less need to
                Fewer dose       increase dosage, shorten intervals, or add
                escalations and  immunosuppressants. These “patches”
                adjunct          raise costs and risks without providing
                therapies
                                 true solutions.
                                 Preventing clinical relapse avoids urgent
                                 care, hospitalizations, surgeries, missed
                Fewer relapses  workdays, and disease progression—
                                 helping maintain stability and lower
                                 system-wide costs.
                                 Early failures in biologics create distrust
                                 and more restrictive payer policies.
                Less payer       Durable options offer predictability,
                friction
                                 supporting value-based care and
                                 improving payer-provider dynamics.
                                 Durable biologics reduce the need for
                Less clinician  frequent switches and administrative
                frustration      battles, restoring clinician confidence
                                 and easing burnout.
                                 Reliable therapies foster patient trust,
                Higher patient   adherence, and proactive health
                trust and        management—positively impacting all
                engagement
                                 stakeholders.


               Durability is not a soft metric.
               It’s not a bonus feature.
               It’s the economic backbone of a biologic that belongs in a
               value-driven healthcare system.







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