Page 63 - Binder2
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The real money is in a drug you can charge thousands for
               not once. Not twice. But every single month. But you have
               to convince the patient they need it.


               These are therapies that demand adherence, persistence,
               and often uncomfortable administration. For them to
               succeed, patients must trust the promise, commit to the
               plan, and remain engaged even when results are slow, or
               side effects emerge. That’s why patient buy-in isn’t
               peripheral—it’s central.

               The branding became more personal, more visual, and
               more emotional. "You don’t have to live like this." "Ask
               your doctor." "Take back control." The imagery was
               universal, uplifting, and strategically silent on the
               complexity behind the scenes.

               But here’s what was rarely included in that story:


                   •  The risk of anti-drug antibodies.
                   •  The possibility of secondary loss of response.
                   •  The reality that many patients would cycle through
                       multiple biologics over time.


               These weren’t marketing oversights—they were strategic
               omissions.


               In public, biologics were precision tools. In practice, they
               were increasingly blunt instruments—administered
               broadly, often without personalized immune monitoring,
               and sometimes without long-term durability. But the
               marketing never changed. It kept selling permanence in a
               system that was built on switches and escalations.


               And patients believed it. Why wouldn’t they?



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