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Does Blood Flow Restriction Therapy Improve Leg Strength in Patients with a Painful Total Knee Arthroplasty ?  10



        Surgery

        Does Blood Flow Restriction Therapy Improve Leg Strength in Patients with a
        Painful Total Knee Arthroplasty ?


        Endorsed by: Dr. Raghav K Barve, Orthopedic Surgeon, Bone and Joint Clinic, Pune


        Background
          Around 20% of patients are unsatisfied with total knee arthroplasty (TKA) because of residual pain.     1

          In 13% of painful TKAs, the cause of pain is unknown and revision without knowing the cause of pain
          is usually unsuccessful. 1



          After TKA, persistent  quadriceps weakness is  associated with development  of flexion  instability
          (FI). 2


          Blood flow restriction (BFR) therapy combines venous occlusion with low-load resistance training
          for the development of muscle strength and hypertrophy.    3



          This  study  investigated  the  effect  of  BFR  with  standard  physiotherapy  (PT)  versus  PT  alone  in
          improving quadriceps and hamstring strength in patients with instability and weakness >1 year after

          primary TKA. 2

                                                         Anaerobic        Increased anabolic
                                                         metabolism          hormones




                                   Metabolic stress                                           Increased muscle
                   Venous                              Cellular swelling  Increased protein
                   occlusion       and mechanical                            synthesis         strength and
                                      tension                                                  hypertrophy

                                                                            Increased
                                                       Induction of type   myogenic stem
                                                        2 muscle fibres
                                                                              cells

                   Fig: Hypothesized mechanism of BFR for development of muscle strength and hypertrophy 2,3


        Methods
                   2


        This study retrospectively reviewed 48 patients       Exclusion criteria
        between July 2016 and January 2019. Patients             Global instability

        were evaluated by joint arthroplasty surgeons.           Prosthetic joint infection
                                                                 Implant loosening
        Inclusion criteria                                       <6 weeks of BFR or PT alone
           FI after TKA

           Primary TKA without prior revision surgery
           Minimum 6 weeks of BFR or PT alone
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