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Journal of Wildlife and Parks, 36: 39-44 (2021)
               Journal of Wildlife and Parks, 36: 39-44 (2021)



                      CASE REPORT: TREATMENT OF TRYPANOSOMES
                   INFESTATION IN A MALAYAN TIGER (Panthera tigris ssp.
                                              jacksoni)

                   *Zubaidah, K., Siti-Suzana, S., Nur-Mala, A., Mohd-Zamri, R.
                                       & Khairul-Anuar, A.L.

                   National Wildlife Rescue Centre (NWRC) Sungkai, Department of
                        Wildlife and National Parks (PERHILITAN) Peninsular
                                   Malaysia, 35600 Sungkai, Perak.

                      *Corresponding author’s email: zubaidah@wildlife.gov.my


                                             ABSTRACT

               A male adult Malayan Tiger (Panthera tigris ssp. jacksoni) was presented with
               clinical signs of decreased appetite, inactive and gradual loss of body weight.
               Diagnosis of trypanosomiasis was made based on thin blood smear examination.
               The  hematology  and  biochemistry  results  revealed  anaemia  and
               hyperproteinaemia  and  present  of  marked  enlargement  of  the  liver  upon
               abdominal  ultrasound.  Early  treatment  with  Immiticide ®   (melarsomine
               dihydrochloride)  only  showed  partial  recovery  of  the  infection.  Follow  up
               treatment  with  two  doses  of  Berenil (diminazene  aceturate)  at  3.5  mg/kg  by
                                                 ®
               intramuscular injection resulted in full recovery.

               Keywords:  Malayan  tiger,  trypanosomes,  melarsomine  dihydrochloride,
               diminazene aceturate

                  Received (19-May-2020); Accepted (11-January-2021); Available online
                                          (25-March-2021).

               Citation:  Zubaidah,  K.,  Siti-Suzana,  S.,  Nur-Mala,  A.,  Mohd-Zamri,  R.  &
               Khairul-Anuar, A.L. (2021). Case report: treatment of trypanosomes infestation in
               a Malayan tiger (Panthera tigris ssp. jacksoni). Journal of Wildlife and Parks, 36:
               39-44.


                                          INTRODUCTION

               Trypanosoma  is  an  extracellular  protozoan  blood  parasite  that  affects  most
               domestic  animals  and  wildlife.  The  major  veterinary  importance  species  are
               Trypanosoma congolense, T.  vivax,  T.  brucei  brucei,  T.  simiae,  T.  evansi,  T.
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