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                                                                                                      hoarding places on this vulnerable population [14].
                                                                                                      of elder neglect or abuse and speaks to the severe impairment
                                                                                                      Furthermore, hoarding in the elderly is characterized as a form
 PERFECTOR
                                                                                                      This complicates efforts to characterize and treat the problem.
                                                                                                      diagnosed for years (up to a decade) after onset of symptoms.
                                                                                                      and hoarding [17-19]. Similar to PTSD, hoarding may not be
                                                                                                    Scientists have linked genetic heritability of PTSD [16]
                                                                                                      years of age [15].
                                                                                                      of the general population, but as high as 6% in people over 55
                                                                                                      every 5 years of life. Hoarding incidence is estimated at 2–4%
                                                                                                      that hoarding prevalence and severity increases by 20% with
                                                                                                      and depression. Furthermore, Cath and colleagues [14] found
                                                                                                      age, and is correlated with social isolation, co-morbid anxiety,
                                                                                                      begins around 40 years of age, increases in severity after middle
                                                                                                      Roane and co-authors [13] concluded that hoarding onset
                                                                                                    In a review of literature on hoarding in elderly populations,
                                                                                                      nection in this population.
                                                                                                      emerging anecdotal reports and related literature suggest a con-
                                                                                                      hoarding and PTSD were found to be correlated [12]. However,
                                                                                                      assessed PTSD among Jewish Holocaust survivors, although
                                                                                                      We did not find any articles in the literature that directly
                                                                                                      HOARDIng AMOng JEwISH HOlOCAuST SuRVIVORS
                                                                                                      adjustments in diagnosis and treatment approach [11].
                                                                                                      largely untreated PTSD symptoms, which are unique, require
                                                                                                      contracted as friends died [11]. As Holocaust survivors age,
                                                                                                      sions, children became independent adults, and social circles
                                                                                                      [3]. However, with aging, individuals retired from their profes-
                                                                                                      origin and developed strong social circles with other survivors
                                                                                                      responsibilities. Most were disconnected from their families of
                                                                                                      with PTSD symptoms by engaging in occupational and family
                                                                                                      for treatment [4]. For years, these untreated individuals coped
                                                                                                      suggest that the latter diagnosis is insufficient to provide a basis
                                                                                                      chopathological symptoms exceed those of PTSD and some
                                                                                                    Furthermore, as Jewish Holocaust survivors age, their psy-
                                                                                                      productive lives.
                                                                                                      Holocaust survivors, despite the fact that most had achieved
                                                                                                      research published in the 1970s [10] identified PTSD among
 KEY WORDS:
 131118-COHANIM - 131118-COHANIM | 2 - B | 18-11-13 | 11:24:13 | SR:-- | Cyan
                                                                                                      phenomenon termed: a collusion of silence [4]. However,
 #131118-COHANIM - 131118-COHANIM | 2 - B | 18-11-13 | 11:24:13 | SR:-- | Black
 131118-COHANIM - 131118-COHANIM | 2 - B | 18-11-13 | 11:24:13 | SR:-- | Yellow
                                                                                                      about their experiences and the world did not want to listen – a
 131118-COHANIM - 131118-COHANIM | 2 - B | 18-11-13 | 11:24:13 | SR:-- | Magenta
                                                                                                      treatment [3,4]. Second, many survivors did not want to talk
                                                                                                      ing with symptoms, affected individuals did not get the proper
                                                                                                      a distinct diagnosis with a treatment strategy. When present-
                                                                                                      ing a time in history when the disorder was not codified into
                                                                                                      several reasons. First, these individuals experienced PTSD dur-
                                                                                                      Holocaust survivors were not assessed or treated for PTSD for
                                                                                                      In the initial years following the end of World War II, Jewish
 2
 1
                                                                                                      pTSD AMOng JEwISH HOlOCAuST SuRVIVORS
                                                                                                      certain traumatic events prior to symptom onset [9].
                                                                                                      highlighted an important association between hoarding and
                                                                                                      nosis, including more instances of physical assault. The authors
 #
 Case CommuniCations  Case CommuniCations  Despite antifungal therapy, the patient’s   FDG PET/CT images showed intensely   change on the corresponding CT images.   of many lesions did not show significant   baseline PET images. The anatomical size   higher FDG uptake compared with the   some of the lesions showing significantly   of the hepatosplenic fungal infection with   PET/CT scans that revealed persistence   he underwent a series of follow-up FDG   clinical conditi
 Pyoderma Gangrenosum and Extensive Aseptic    although with the drawbacks of being neither inexpensive nor   COnCluSIOnS
 Chest Wall Abscess in a Patient with Inflammatory   free of morbidity. In more recent years, guided biopsies have   Surgical lymph node biopsy, if performed correctly, is likely
                                                          to yield an optimal diagnostic result. However, in view of
          become the gold standard for tissue sampling since they are
 Bowel Disease  cost-effective and involve a simple and minimally invasive   the invasive nature of the procedure, such biopsies should be
                                                          undertaken only in patients with a definitive indication or with
          procedure that is associated with low morbidity. These proce-
          dures may provide rapid information and direct approach when   a high suspicion for lymphoma. The first percutaneous biopsy
 Igor Snast MD , Iris Ostfeld MD , Lev Pavlovsky MD PhD , Emmilia Hodak MD  and Anat Gafter-Gvili MD 2,3,4  facing a patient presenting with lymphadenopathy. Guided   result can be uninformative, especially in patients with a his-
 1,4
 1
 1
 2
          biopsies can be used on palpable or non-palpable lymph   tory of lymphoma; however, occasionally the type of lymphoma
 2
 1
 Departments of  Dermatology and  Medicine A, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel   nodes. In the latter case, different techniques can be used,   cannot be accurately determined. In these situations, repeated
 3 Institute of Hematology, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel
 4 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel  such as endoscopic ultrasound-guided fine-needle aspiration   percutaneous biopsies should be avoided and patients should
          (EUS-FNA), endobronchial ultrasound-guided transbronchial   be referred for surgery.
          needle aspiration (EBUS-TBNA), and abdominal or thoracic
          CT-guided biopsy. Needle biopsy is quick, does not require a   Acknowledgment
          general anesthetic, can be performed ambulatory, and has high   The authors acknowledge the statistical assistance of Ms. Ronit Leiba
 computed tomography (CT) scan depicted   the thigh and chest wound revealed a diffuse   overall sensitivity and specificity with low false-negative and   MA, statistician, Quality of Care Unit, Rambam Health Care Campus,
 KEY WORDS:  aseptic abscess, inflammatory   a large subcutaneous chest wall abscess   dermal infiltrate of neutrophils extending   false-positive results [13-18].  Haifa, Israel
 bowel disease (IBD), neutrophilic   extending within the pectoralis muscle   into chest wall striated muscles, with focal   In our study, 52 patients (44.1%) underwent percutaneous
 dermatosis, neutrophils, pyoderma   with sternal destruction. An incision was   fibrinoid necrosis of blood vessel walls.   biopsy prior to surgical consultation. Of these, 33 underwent   Correspondence
                                                          Dr. y. Kluger
 gangrenosum (PG)  performed with drainage of purulent fluid.   Laboratory evaluation demonstrated   core-needle biopsy (FNB) only, 16 both FNA and FNB, and 3   Dept. of General Surgery, Rambam Health Care Campus, Haifa 3109601, Israel
 IMAJ 2018; 20: 712–713  Broad-spectrum antibiotics were initiated.   elevated inflammatory markers; negative   FNA only. Since the most common pathologic diagnosis was   fax: (972-4) 777-3527
 Near the chest wound, two satellite rapidly   serologies for hepatitis B/C, human immu-  lymphoma, we decided to review the sensitivity and specificity   email: y_kluger@rambam.health.gov.il
 enlarging ulcers with undermined viola-  nodeficiency virus, cytomegalovirus, and   of percutaneous biopsy for detection of lymphoma. Our results   References
 ceous borders appeared.   atypical bacteria; negative Mantoux and   contrast the published literature, which reported higher sensi-  1.  Zornoza J, Cabanillas FF, Altoff TM, Ordonez N, Cohen MA. Percutaneous needle
 yoderma gangrenosum (PG) is a rare   Due to progressive chest wall necrolysis   QuantiFERON tests; negative blood, skin,   tivity and specificity of percutaneous core-needle biopsy for the   biopsy in abdominal lymphoma. AJR Am J Roentgenol 1981; 136 (1): 97-103.
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 50% of patients with PG have an anteced-  [Figure 1A]. On the thigh, an erythematous   reaction.   just two false-positive and seven false-negative biopsy results,   reliable. J Clin Oncol 1996; 14 (9): 2431-4.
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 collections of neutrophils, clinically mim-  [B] Close up view of pyoderma gangrenosum of left thigh  cantly higher local treatment failure rate, which may in turn be   8.  Williamson HA, Jr. Lymphadenopathy in a family practice: a descriptive study of
                                                            249 cases. J Fam Pract 1985; 20 (5): 449-52.
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 that time, she was being treated with 0.5   results are particularly noteworthy if we consider that every   and neck clinic: a clinically beneficial and cost-effective service. Cytopathology
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