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A28    SCIENCE
                Tuesday 19 November 2019
            Old dogs, new tricks: 10,000 pets needed for science




            By CARLA K. JOHNSON                                                                                                 that varies by breed. Large
            AP Medical Writer                                                                                                   dogs have shorter lifespans
            SEATTLE  (AP)  —  Can  old                                                                                          than smaller dogs.
            dogs  teach  us  new  tricks?                                                                                       A  Great  Dane’s  lifespan
            Scientists  are  looking  for                                                                                       is  about  half  that  of  a  toy
            10,000 pets for the largest-                                                                                        poodle’s.
            ever  study  of  aging  in  ca-                                                                                     That makes large dogs bet-
            nines.  They  hope  to  shed                                                                                        ter test subjects for the pill.
            light  on  human  longevity                                                                                         Dogs  weighing  at  least  40
            too.                                                                                                                pounds  will  be  eligible  for
            The  project  will  collect  a                                                                                      an  experiment  with  rapa-
            pile of pooch data: vet re-                                                                                         mycin,  now  taken  by  hu-
            cords,  DNA  samples,  gut                                                                                          mans  to  prevent  rejection
            microbes  and  information                                                                                          of  transplanted  kidneys.
            on  food  and  walks.  Five                                                                                         The  drug  has  extended
            hundred dogs will test a pill                                                                                       lifespan  in  mice.  A  small
            that  could  slow  the  aging                                                                                       safety study in dogs found
            process.                                                                                                            no dangerous side effects,
            “What we learn will poten-                                                                                          said  project  co-director
            tially be good for dogs and                                                                                         Matt Kaeberlein of the Uni-
            has great potential to trans-                                                                                       versity of Washington.
            late to human health,” said                                                                                         Human  devotion  to  dogs
            project  co-director  Daniel                                                                                        drives projects like this, the
            Promislow  of  the  University   In  this  Monday,  Nov.  11,  2019  photo,  University  of  Washington  School  of  Medicine  researcher   scientists  said.  Owners  will
            of  Washington  School  of   Daniel Promislow, the principal investigator of the Dog Aging Project grant, rubs the head of his   gladly fill out surveys, send
            Medicine.                    elderly dog Frisbee at their home in Seattle.                                          records and submit a pup’s
            If  scientists  find  a  genetic                                                                   Associated Press  poop  for  analysis  if  they
            marker  for  a  type  of  can-  welfare advisers.         The data collected will be  can, should we?”              think it will help all dogs live
            cer  in  dogs,  for  instance,  To  nominate  a  pet,  own-  available to all scientists.  Compared  to  farm  dogs  longer, even if it won’t help
            that  could  be  explored  in  ers can visit the Dog Aging  Leslie  Lambert  of  Parkville,  in  the  past,  today’s  pam-  their pet.
            humans.                      Project’s website.           Maryland,    enrolled   her  pered pups live longer and  “People  love  dogs,”  said
            For the study, the dogs will  The  five-year  study  was  11-year-old  rescue  dog,  get more geriatric diseases,  Promislow,  who  normally
            live  at  home  and  follow  formally  launched  Thurs-   Oscar, in an early phase.    said  veterinarian  Dr.  Kate  studies  aging  in  fruit  flies.
            their usual routine. All ages  day  at  a  science  meeting  “I  would  selfishly  like  to  Creevy  of  Texas  A&M  Uni-  “No  one  has  ever  come
            and  sizes,  purebreds  and  in  Austin,  Texas.  The  Na-  have him around forever,”  versity,  the  project’s  chief  up to me and said, ‘Oh my
            mutts are welcome.           tional  Institute  on  Aging  is  said the 33-year-old veteri-  scientific officer.    goodness,  I  just  love  fruit
            Owners  will  complete  pe-  paying  for  the  $23  million  narian.  “Unfortunately,  he  Yet  no  standard  measures  flies.’”
            riodic  online  surveys  and  project because dogs and  ages  much,  much  faster  exist  for  frailty  or  prognosis  Promislow’s  mixed  breed,
            take  their  dogs  to  the  vet  humans  share  the  same  than I do.”                 in sick, aged dogs, Creevy  14-year-old Frisbee, will not
            once a year, with the pos-   environment, get the same  But  she’s  torn  by  the  pros-  said. The project will devel-  participate  to  prevent  a
            sibility of extra visits for cer-  diseases and dogs’ shorter  pect  of  an  anti-aging  pill  op those tools.      conflict of interest.
            tain  tests.  Their  welfare  will  lifespans  allow  quicker  re-  because  so  many  aban-  One  dog  year  is  roughly  “It’s too bad because she’s
            be monitored by a bioethi-   search  results,  said  deputy  doned  dogs  go  without  equal  to  seven  human  a terrific example of a real-
            cist and a panel of animal  director, Dr. Marie Bernard.  care.  “Just  because  we  years,  Creevy  said,  but  ly healthy ager,” he said.q

                                                                      China tests Mars lander in international

                                                                      cooperation push



                                                                      By SAMUEL McNEIL                           It has developed rapidly, especially since it
                                                                      Associated Press                           conducted its first crewed mission in 2003,
                                                                      HUAILAI, China (AP) — China showed off  and  has  sought  cooperation  with  space
                                                                      its  Mars  spacecraft  during  a  landing  test  agencies from Europe and elsewhere.
                                                                      Thursday  as  the  country  pushes  for  inclu-  The U.S., however, has banned most space
                                                                      sion in more global space projects.        cooperation with China out of national se-
             In this Nov. 14, 2019, photo, a lander is lifted during a test of   The  demonstration  of  hovering,  obstacle  curity concerns, keeping China from par-
             hovering, obstacle avoidance and deceleration capabilities at
             a facility in Huailai in China's Hebei province, Thursday, Nov.   avoidance and deceleration capabilities  ticipating  in  the  International  Space  Sta-
             14, 2019.                                                was  conducted  at  a  site  outside  Beijing  tion.
                                                     Associated Press  simulating  conditions  on  the  red  planet,  Despite  that,  China’s  ambitions  continue
                                                                      where the pull of gravity is about one-third  to grow as it seeks to rival the U.S., Russia
                                                                      that of Earth.                             and Europe in space and cement its posi-
                                                                      China plans to launch a lander and rover  tion as a regional and global power. It is
                                                                      to Mars next year to explore parts of the  gradually constructing its own larger, more
                                                                      planet,  one  of  four  scheduled  missions.  permanent space station in which it has in-
                                                                      The U.S. and Europe are also sending rov-  vited foreign participation.
                                                                      ers to Mars next year, and the United Arab  The lander on Thursday successfully avoid-
                                                                      Emirates plans to launch an orbiter.       ed  ground  obstacles  during  a  simulated
                                                                      China's   burgeoning    space   program  low-gravity  descent,  according  to  the
                                                                      achieved a lunar milestone earlier this year  China  Aerospace  Science  and  Technol-
                                                                      by landing a spacecraft on the mysterious  ogy Corporation, the Chinese space pro-
                                                                      far side of the moon.                      gram’s main contractor.q
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