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A12   HEALTH
                     Tuesday 19 april 2022
                                                                      Doctors suggest new names for


                                                                      low-grade prostate cancer



                                                                                                                                In  the  U.S.,  about  60%  of
                                                                                                                                low-risk  patients  choose
                                                                                                                                active  surveillance.  But
                                                                                                                                they might still worry.
                                                                                                                                "I would be over the moon
                                                                                                                                if  people  came  up  with  a
                                                                                                                                new  name  for  Gleason  6
                                                                                                                                disease,"  Penson  said.  "It
                                                                                                                                will  allow  a  lot  of  men  to
                                                                                                                                sleep better at night."
                                                                                                                                But  Dr.  Joel  Nelson  of  Uni-
                                                                                                                                versity of Pittsburgh School
                                                                                                                                of Medicine, said dropping
                                                                                                                                the  word  "cancer"  would
                                                                                                                                "misinform   patients   by
                                                                      This  1974  microscope  image  made  available  by  the  Centers   telling  them  there's  noth-
                                                                      for  Disease  Control  and  Prevention  shows  changes  in  cells   ing  wrong.  There's  noth-
                                                                      indicative of adenocarcinoma of the prostate.             ing  wrong  today,  but  that
                                                                                                               Associated Press  doesn't  mean  we  don't
                                                                      By CARLA K. JOHNSON          of  the  disease  can  cause   have to keep track of what
                                                                      AP Medical Writer            some patients to overreact   we've discovered."
                                                                      A cancer diagnosis is scary.  and opt for unneeded sur-   Name changes have hap-
                                                                      Some  doctors  say  it's  time  gery or radiation.        pened previously in low-risk
                                                                      to rename low-grade pros-    Others  agree.  "If  you  re-  cancers  of  the  bladder,
                                                                      tate  cancer  to  eliminate  duce anxiety, you'll reduce   cervix and thyroid. In breast
                                                                      the alarming C-word.         overtreatment,"  said  Dr.   cancer, there's an ongoing
                                                                      Cancer     cells   develop  David Penson of Vanderbilt    debate  about  dropping
                                                                      in  nearly  all  prostates  as  University.  "The  word  'can-  "carcinoma"  from  DCIS,  or
                                                                      men  age,  and  most  pros-  cer,' it puts an idea in their   ductal carcinoma in situ.
                                                                      tate cancers are harmless.  head:  'I  have  to  have  this   In  prostate  cancer,  the
                                                                      About  34,000  Americans  treated.'"                      1960s-era  Gleason  rank-
                                                                      die  from  prostate  cancer  Diagnosis  sometimes  starts   ing  system  has  evolved,
                                                                      annually,  but  treating  the  with  a  PSA  blood  test,   which  is  how  6  became
                                                                      disease can lead to sexual  which  looks  for  high  lev-  the  lowest  score.  Patients
                                                                      dysfunction  and  inconti-   els  of  a  protein  that  may   may assume it's a medium
                                                                      nence.                       mean cancer but can also     score on a scale of 1 to 10.
                                                                      Changing the name could  be  caused  by  less  serious    In fact, it's the lowest on a
                                                                      lead more low-risk patients  prostate problems or even    scale of 6 to 10.
                                                                      to skip unnecessary surgery  vigorous exercise.           What  to  call  it  instead  of
                                                                      and radiation.               When a patient has a sus-    cancer? Proposals include
                                                                      "This is the least aggressive,  picious  test  result,  a  doc-  IDLE  for  indolent  lesion  of
                                                                      wimpiest  form  of  prostate  tor  might  recommend  a    epithelial  origin,  or  INERRT
                                                                      cancer that is literally inca-  biopsy, which involves tak-  for indolent neoplasm rare-
                                                                      pable of causing symptoms  ing  samples  of  tissue  from   ly requiring treatment.
                                                                      or spreading to other parts  the  prostate  gland.  Next,   "I  don't  really  give  a  hoot
                                                                      of the body," said University  a pathologist looks under a   what  it's  called  as  long
                                                                      of  Chicago  Medicine's  Dr.  microscope and scores the   as  it's  not  called  cancer,"
                                                                      Scott Eggener, who is reviv-  samples for how abnormal    Eggener said.
                                                                      ing a debate about how to  the cells look.                Steve Rienks, a 72-year-old
                                                                      explain  the  threat  to  wor-  Often,  doctors  offer  pa-  civil engineer in Naperville,
                                                                      ried patients.               tients with the lowest score   Illinois, was diagnosed with
                                                                      The words "You have can-     —  Gleason  6  —  a  way  to   Gleason 6 prostate cancer
                                                                      cer"  have  a  profound  ef-  avoid  surgery  and  radia-  in  2014.  He  chose  active
                                                                      fect  on  patients,  Eggener  tion:  active  surveillance,   surveillance, and follow-up
                                                                      wrote  Monday  in  Journal  which involves close moni-    biopsies  in  2017  and  2021
                                                                      of  Clinical  Oncology.  He  toring  but  no  immediate   found no evidence of can-
                                                                      and his co-authors say fear  treatment.                   cer.
                                                                                                                                Calling  it  something  else
                                                                                                                                would help patients make
                                                                                                                                informed  choices,  Rienks
                                                                                                                                said, but that's not enough:
                                                                                                                                Patients need to ask ques-
                                                                                                                                tions  until  they  feel  confi-
                                                                                                                                dent.
                                                                                                                                "It's  about  understanding
                                                                                                                                risk,"  Rienks  said.  "I  would
                                                                                                                                encourage     my    fellow
                                                                                                                                males  to  educate  them-
                                                                                                                                selves  and  get  additional
                                                                                                                                medical opinions."q
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