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A28    SCIENCE
                       Friday 11 May 2018
            Study finds little bang for the buck in Zika blood testing




            By MIKE STOBBE                                                                                                      done by the American Red
            AP Medical Writer                                                                                                   Cross,  which  collects  42
            NEW YORK (AP) — Screen-                                                                                             percent  of  the  U.S.  blood
            ing blood donations for the                                                                                         supply.  They  focused  on
            Zika virus netted only a few                                                                                        donations  from  the  Lower
            infections at a cost of more                                                                                        48 states from June 2016 to
            than  $5  million  for  each                                                                                        September 2017.
            positive test result, accord-                                                                                       Health  officials  say  there
            ing to new research.                                                                                                have been four transfusion-
            The study was the first large                                                                                       related Zika cases reported
            look at the impact of guide-                                                                                        in  Brazil,  but  none  in  the
            lines  set  two  years  ago,                                                                                        United States.
            when  the  Zika  epidemic                                                                                           The  FDA  has  never  before
            was an unfolding menace                                                                                             revoked  a  recommenda-
            in  the  U.S.  and  health  of-                                                                                     tion  to  test  blood  dona-
            ficials  were  scrambling  to                                                                                       tions for a potentially harm-
            prevent new infections.                                                                                             ful  germ,  and  it’s  unlikely
            The     study,   published                                                                                          the agency would do that
            Wednesday  by  the  New                                                                                             now, experts said.
            England  Journal  of  Medi-                                                                                         But  the  agency  could  call
            cine, found that the blood                                                                                          for  a  less  intensive  screen-
            donation  testing  require-                                                                                         ing  called  mini-pool  test-
            ments  offered  little  bang                                                                                        ing.  Rather  than  running
            for  the  buck.  It  also  raised                                                                                   a  test  on  each  separate
            questions  about  whether                                                                                           donor, mini-pool testing in-
            a cheaper testing method                                                                                            volves mixing samples from
            should be used.                                                                                                     16  donors  and  testing  the
            In more than 4 million blood                                                                                        batch. When a batch tests
            donations  checked  in  the                                                                                         positive,  individual  testing
            United  States,  nine  tested   This  2016  digitally-colorized  electron  microscope  image  made  available  by  the  Centers  for   is done to find the tainted
            positive for the Zika virus. Of   Disease Control and Prevention shows the Zika virus, in red, about 40 nanometers in diameter.  donation.
            those,  three  were  consid-  Latin America and the Ca-   spread  through  transfu-    the necessity for it,” said Dr.  That’s  what’s  done  with
            ered an infection threat.    ribbean  in  2015  and  2016,   sions,  the  U.S.  Food  and  Darrell Triulzi, a University of  West  Nile  virus  and  other
            “We can’t afford to spend  with  a  few  very  small  out-  Drug Administration in 2016  Pittsburgh transfusion medi-  germs, experts said.
            that kind of money to find a  breaks in the southern Unit-  called  on  all  blood  banks  cine specialist.         Mini-pool   testing   would
            single case,” said Dr. W. Ian  ed States. The virus is mainly   to screen for it.      The  new  study  is  the  first  cut the cost of Zika testing
            Lipkin,  a  Columbia  Univer-  spread by tropical mosqui-  “The  risk  from  transfusion  large  one  to  evaluate  in half, said Susan Stramer,
            sity  infectious  diseases  ex-  toes, but scientists also dis-  was poorly known. We put  whether  the  testing  made  one  of  the  study’s  authors
            pert who was not involved  covered  some  infections      this  testing  in  place  as  a  sense, he added.         and  vice  president  of  sci-
            in the research.             were spread through sex.     precaution  without  really  The  researchers  looked  at  entific  affairs  at  the  Red
            Zika infections swept across  Fearing  Zika  might  also   having  solid  data  about  the  results  of  screenings  Cross.q
            Cancer docs feel unprepared, but recommend marijuana anyway



                                                                      By CARLA K. JOHNSON          and  simple,”  said  Dr.  Ilana  knowledge to do so.
                                                                      AP Medical Writer            Braun of Dana-Farber Can-    “They’re not as close-mind-
                                                                      SEATTLE (AP) — Nearly half  cer Institute in Boston, who  ed as you might think, and
                                                                      of U.S. cancer doctors who  led  the  study  published  they also feel they have a
                                                                      responded to a survey say  Thursday  in  the  Journal  of  lot to learn,” Braun said.
                                                                      they’ve  recently  recom-    Clinical Oncology.           The  survey  was  conduct-
                                                                      mended  medical  mari-       Patients want to know what  ed in a random sample of
                                                                      juana to patients, although  their  doctors  think  about  cancer  doctors;  research-
                                                                      most  say  they  don’t  know  using marijuana. In the new  ers  got  completed  surveys
                                                                      enough  about  medicinal  study, cancer doctors said  from 237 doctors, or 63 per-
                                                                      use.                         their  conversations  about  cent.
                                                                      The results reflect how mari-  marijuana  were  almost  al-  Marijuana is considered an
                                                                      juana policy in some states  ways  started  by  patients  illegal  drug  by  federal  of-
            This Sept. 15, 2015 file photo shows marijuana plants a few weeks
            away from harvest in a medical marijuana cultivation center in   has  outpaced  research,  and  their  families,  not  by  ficials  and  federal  restric-
            Albion, Ill.                                              the  study  authors  said.  the doctors themselves.       tions have limited research.
                                                     Associated Press  All  29  states  with  medical  Overall,  nearly  eight  in  10  Last  year,  the  National
                                                                      marijuana  programs  allow  cancer  doctors  reported  Academies  of  Sciences,
                                                                      doctors  to  recommend  it  having    discussed   mari-   Engineering  and  Medicine
                                                                      to cancer patients. But no  juana with patients or their  concluded the lack of sci-
                                                                      rigorous  studies  in  cancer  families,  with  46  percent  entific  information  about
                                                                      patients  exist.  That  leaves  recommending  it  for  pain  marijuana  poses  a  risk  to
                                                                      doctors  to  make  assump-   and  other  cancer-related  public health.
                                                                      tions  from  other  research  problems  to  at  least  one  There’s  evidence  marijua-
                                                                      on    similar   prescription  patient in the past year.   na  can  treat  chronic  pain
                                                                      drugs,  or  in  other  types  of  Among  those  who  said  in  adults  and  medications
                                                                      patients.                    they  recommended  mari-     similar  to  marijuana  can
                                                                      “The  big  takeaway  is  we  juana,  56  percent  said  ease nausea from chemo-
                                                                      need more research, plain  they did not have sufficient  therapy. q
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