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A32    FEATURE
                        Friday 27 July 2018
            Study: Lowering blood pressure helps prevent mental decline




            By MARILYNN MARCHIONE                                                                                               "It's really more important to
            CHICAGO (AP) — Lowering                                                                                             prevent  MCI  than  demen-
            blood  pressure  more  than                                                                                         tia  in  some  ways.  It's  like
            usually  recommended  not                                                                                           preventing high cholesterol
            only  helps  prevent  heart                                                                                         rather than a heart attack,"
            problems,  it  also  cuts  the                                                                                      Williamson said.
            risk  of  mental  decline  that                                                                                     There  also  were  fewer  de-
            often  leads  to  Alzheimer's                                                                                       mentia  cases  in  the  in-
            disease, a major study finds.                                                                                       tensive-treatment   group
            It's the first time a single step                                                                                   but  there  were  too  few  to
            has been clearly shown to                                                                                           say  lower  blood  pressure
            help  prevent  a  dreaded                                                                                           was  the  reason.  Dementia
            condition  that  has  had                                                                                           takes  longer  to  develop
            people  trying  crossword                                                                                           than mild impairment does,
            puzzles,  diet  supplements                                                                                         so  doctors  think  the  differ-
            and a host of other things in                                                                                       ence may widen over time.
            hope of keeping their mind                                                                                          MRI  scans  on  454  partici-
            sharp.                                                                                                              pants  showed  that  those
            In  the  study,  people  treat-                                                                                     in the lower pressure group
            ed to a top blood pressure                                                                                          had  less  white  matter  le-
            reading  of  120  instead  of                                                                                       sions — areas of scarring or
            140  were  19  percent  less                                                                                        damage  from  injury,  such
            likely to develop mild cog-                                                                                         as  inadequate  blood  sup-
            nitive impairment. They also                                                                                        ply.
            had  fewer  signs  of  dam-  Margaret  Graham,  74,  has  her  blood  pressure  checked  while  visiting  the  Wake  Forest  Baptist   "It  matches"  the  other  re-
            age  on  brain  scans,  and   Medical Center in Winston-Salem, N.C., on Friday, July 13, 2018.                      sults  on  thinking  skills  and
            there was a possible trend                                                                         Associated Press  bolsters  the  evidence  that
            toward fewer cases of de-                                                                                           lowering  blood  pressure
            mentia.                      rather  than  140.  Normal  is  Half got two medicines, on  and  deaths.  But  tests  of  helps,  said  Laurie  Ryan,  a
            "This is a big breakthrough,"  under 120.                 average,  to  get  their  top  thinking  skills  continued  for  dementia  scientist  at  the
            said  Dr.  Jeff  Williamson  of  High pressure can damage  reading below 140. The rest  two more years, and these  National Institute on Aging.
            Wake  Forest  Baptist  Medi-  blood vessels and has long  got  three  drugs,  on  aver-  new  results  were  revealed  HOW LOW TO GO?
            cal  Center  in  North  Caro-  been linked to a higher risk  age,  and  aimed  for  120.  on Wednesday.             This  study's  previous  results
            lina.  "It's  more  important  for  dementia.  But  it's  not  During  the  study,  the  top  Researchers saw a 19 per-  led  to  last  fall's  guidelines
            than ever to work with your  been  known  if  lowering  pressure  averaged  121  in  cent lower risk of mild cog-   change,  setting  high  pres-
            physician  to  ensure  that  pressure would reduce that  the      intensive-treatment  nitive  impairment,  or  MCI,  sure  at  130.  Some  doctors
            you have good blood pres-    risk  or  by  how  much.  The  group and 135 in the other  in  the  intensive-treatment  have  criticized  that  as  too
            sure control."               federally funded study was  group.                        group  —  285  cases  versus  aggressive,  but  the  new
            He led the study and gave  designed to test this in the  The  study  was  stopped  in  348  in  the  higher  pressure  results,  showing  benefits
            results  Wednesday  at  the  most rigorous way.           2015, nearly two years ear-  group.  About  half  of  peo-  to  the  brain,  "support  and
            Alzheimer's  Association  In-  ABOUT THE STUDY            ly,  when  it  became  clear  ple  with  MCI  develop  de-  maybe  even  extend  the
            ternational  Conference  in  It involved more than 9,300  that lower pressure helped  mentia  over  the  next  five  guidelines," Williamson said.
            Chicago.  They're  consid-   people  with  high  pressure.  prevent  heart  problems  years.                        "The  goal  of  below  130  is
            ered  preliminary  until  pub-                                                                                      extremely important."
            lished,  expected  later  this                                                                                      The study did not test spe-
            year.                                                                                                               cific  blood  pressure  drugs.
            Independent         experts                                                                                         Instead, each participant's
            cheered the news.                                                                                                   doctor  chose  which  ones
            "We have long known that                                                                                            to use from the more than
            high blood pressure is bad                                                                                          a dozen available.
            for  your  heart.  Now  we're                                                                                       When the heart results were
            also  learning  it's  bad  for                                                                                      announced  a  few  years
            your  brain,"  said  James                                                                                          ago,  doctors  said  that
            Hendrix,  director  of  global                                                                                      too-low  pressure,  fainting
            science initiatives at the Al-                                                                                      episodes and some kidney
            zheimer's Association.                                                                                              problems were a little more
            THE  BRAIN-BLOOD  PRES-                                                                                             common  in  the  intensively
            SURE LINK                                                                                                           treated  group  but  that
            About  50  million  people                                                                                          those risks were considered
            worldwide have dementia,                                                                                            worth the benefits of a low-
            and Alzheimer's is the most                                                                                         er risk of heart trouble and
            common  type.  There  is  no                                                                                        death.
            cure  —  current  medicines                                                                                         Getting  to  the  lower  level
            such  as  Aricept  and  Na-                                                                                         meant  using  one  more
            menda just ease symptoms                                                                                            medicine,  and  "90  per-
            — so prevention is key.                                                                                             cent  of  these  are  generic
            Roughly  half  of  adults  in                                                                                       and  cost  less  than  a  dol-
            the  United  States  have                                                                                           lar a day," Williamson said.
            high  blood  pressure  under                                                                                        "For  a  modest  cost  this
            guidelines  adopted  last    A cognitive test sheet completed by a study participant sits on an examination room table at   has  a  tremendously  im-
            year that define it as a top   Wake Forest Baptist Medical Center in Winston-Salem, N.C., on Friday, July 13, 2018.   portant  health  benefit  for
            number  of  130  or  more,                                                                         Associated Press  people."q
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