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SCIENCEThursday 4 February 2016

Scientists map bedbug genome, follow pest through NYC subway 

VERENA DOBNIK                   In this March 30, 2011, file photo, a bedbug is displayed at the Smithsonian Museum in Wash-                                         research team at 36 institu-
Associated Press                ington.                                                                                                                              tions, including the Univer-
NEW YORK (AP) — Scien-                                                                                                                                               sity of Cincinnati.
tists have mapped the                                                                                                                             Associated Press   The New York team’s re-
genome of bedbugs in                                                                                                                                                 sulting scientific paper on
New York City, then traced      ations between the Upper  Geneticist Christopher Ma-     bug project.                                                                the subject was published
fragments of the nefarious      East Side and Upper West  son, who worked on the         He says New York’s bed-                                                     Tuesday in Nature Commu-
pests’ DNA through the          Side.                     project, says the reason for   bugs “move around with                                                      nications. A second paper
subway system.                                            that can be found simply by    people, dogs, and peo-                                                      on bedbug genetics, from
In the grubby recesses of                                 looking at a subway map:       ple’s items — and they                                                      the University of Cincinnati,
hundreds of stations, they                                In Manhattan, for instance,    probably move most eas-                                                     also appeared Tuesday in
discovered surprising ge-                                 subway lines run the length    ily the way people move                                                     the same publication.
netic diversity among the                                 of the island north to south,  most easily.”                                                               To learn how the bedbug
bloodsucking creatures.                                   while there’s no subway        Amato collaborated with                                                     has evolved and spread,
The next step is to figure out                            link through Central Park      Mason, who works at Weill                                                   the New York team took
how the information can                                   between the East Side and      Cornell Medicine’s Institute                                                DNA sample swabs from
be put to good use, such                                  the West Side.                 for Computational Bio-                                                      1,400 city locations includ-
as to develop better insec-                               Not that bedbugs are riding    medicine.                                                                   ing subway cars, turnstiles,
ticides or blood thinners.                                the subway, noted George       A bedbug colony at the                                                      ticket vending kiosks, and
But these goals will take fur-                            Amato, an evolutionary         famed museum was used                                                       above ground places like
ther medical research.                                    biologist at the American      for the genome map. A                                                       parks.
For now, the focus is on two                              Museum of Natural History      similar map was assem-                                                      Amato said there are many
main players in New York                                  who also worked on bed-        bled by an international                                                    ways small fragments of
life: the subway and bed-                                                                                                                                            the insects’ DNA, or DNA
bugs.                                                                                                                                                                of a related species, could
Scientists already have                                                                                                                                              get into the subway —
found that genetic trac-                                                                                                                                             clinging to the clothes of
es of bedbugs in north-                                                                                                                                              some of the 6 million daily
ern Manhattan are more                                                                                                                                               riders and their belongings,
closely related to those in                                                                                                                                          or washed down into the
the island’s southern part,                                                                                                                                          stations.
while there are bigger vari-                                                                                                                                         Amato said the first rough
                                                                                                                                                                     bedbug genetic sequence
                                                                                                                                                                     emerged about a year
                                                                                                                                                                     ago, but it took months to
                                                                                                                                                                     refine the model into an
                                                                                                                                                                     accurate genome.
                                                                                                                                                                     “Before this, people were
                                                                                                                                                                     just feeling their way
                                                                                                                                                                     through in the dark; this
                                                                                                                                                                     genome turns the light on
                                                                                                                                                                     for various areas of other
                                                                                                                                                                     research,” said Amato.
                                                                                                                                                                     “Our team is now moving
                                                                                                                                                                     on to the genetics of cock-
                                                                                                                                                                     roaches and other living
                                                                                                                                                                     fossils.”q
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