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SCIENCEFriday 15 January 2016

Task force: Mammograms an option at 40, do more good at 50 

L. NEERGAARD                     found.                        ports a range of options”        their own choice.               the University of California,
AP Medical Writer                The advisory group wants      for 40-somethings, LeFevre                                       San Francisco. “Maybe we
WASHINGTON (AP) — Mam-           younger women to under-       said.                            “We’re moving away from         should be screening in a
mograms do the most good         stand the trade-offs before                                                                    new way.”
later in life, a U.S. govern-    deciding: Among every         DIFFERING GUIDELINES             paternalistic      medicine     Esserman leads the first-
ment task force declared         1,000 women screened,         Mammograms aren’t per-                                           of-its-kind WISDOM study
this week in recommending        one additional death          fect, and different health       where we doctor organiza-       that soon will begin enroll-
that women get one every         could be prevented by         organizations weigh the                                          ing 100,000 women to test
other year starting at age       starting mammograms at        trade-offs differently. So       tions used to tell women,       whether tailoring screening
50. It said 40-somethings                                                                                                       to someone’s individual risk
should make their own                                                                           ‘You must do this,’” Braw-      is better than age-based
choice after weighing the                                                                                                       mammograms. Women
pros and cons.                                                                                  ley said. “We’re saying,        given annual mammo-
When to start routine mam-                                                                                                      grams starting at 40 will
mograms and how fre-                                                                            ‘This woman is at higher        be compared with others
quently to get them has                                                                                                         assigned more or less fre-
long been controversial.                                                                        risk, therefore maybe she       quent screenings, starting
The latest guidelines from                                                                                                      at different ages, based on
the U.S. Preventive Services                                                                    should get screened at 40.      in-depth risk assessments.
Task Force stick with its ad-
vice that women should                                                                          This woman is at lower risk,    INSURANCE COVERAGE
one every two years be-                                                                                                         Insurance usually pays for
tween ages 50 and 74. But                                                                       maybe she can wait a little     mammograms. Because
they also make clear that                                                                                                       of concern about how the
it’s an option for young-                                                                       later.’”                        task force recommenda-
er women even though                                                                                                            tions might be implement-
they’re less likely to benefit.                                                                 The American College of         ed, Congress recently ex-
Some health groups urge                                                                                                         tended for two years leg-
mammograms every year                                                                           Obstetricians and Gyne-         islation preserving access
starting at 40 — although                                                                                                       to routine mammograms
last year the American                                                                          cologists stands by annual      without copays starting at
Cancer Society upped its                                                                                                        age 40.
starting age to 45.                                                                             mammograms starting at
There is some common                                                                                                            WHEN TO STOP
ground emerging, that                                                                           40, while urging patient        The task force says more
mammography advice                                                                                                              research is needed to
shouldn’t always be one-                                                                        education and shared de-        know whether to continue
size-fits all. “Age 50 isn’t                                                                                                    mammograms at 75 and
magic,” said task force                                                                         cision-making.                  beyond. The cancer soci-
past chairman Dr. Michael                                                                                                       ety says to keep screening
LeFevre of the University of     A radiologist uses a magnifying glass to check mammograms      THINGS TO CONSIDER              as long as women are in
Missouri.                        for breast cancer in Los Angeles. Mammograms do the most       More than 200,000 women         good health and have a
Here are some things to          good later in life, a government task force said this week in  in the U.S. are diagnosed       life expectancy of at least
know about mammo-                recommending that women get one every other year starting      with breast cancer each         10 years.
grams.                           at age 50, and that 40-somethings make their own choice after  year, and about 40,000 die
                                 weighing the pros and cons.                                    from it. It is most frequently  WHAT’S NEXT
WHAT THE TASK FORCE SAYS         (AP Photo/Damian Dovarganes)                                   diagnosed among wom-            The task force said more
Women in their 60s are the                                                                      en ages 55 to 64, and the       research is needed to tell
most likely to avoid dying       40 instead of 50. But there   do women and their physi-        median age of death from        if newer 3-D mammograms
from breast cancer thanks        would be 576 more false       cians.                           breast cancer is 68.            should be used for routine
to mammograms, but               alarms and 58 additional      The American Cancer So-          Screening guidelines are        screening and if women
there’s clearly enough ben-      unneeded biopsies. Also,      ciety says to begin annual       only for women at aver-         with dense breasts benefit
efit for the average woman       two extra women would be      mammograms at 45 but             age risk of breast cancer.      from extra testing, such as
to start at 50, the task force   overdiagnosed, treated for    switch to every other year       Women with a mother, sis-       with ultrasounds or MRIs.q
                                 cancer that never would       at 55. After menopause,          ter or daughter with breast
                                 have become life-threat-      tumors tend to grow more         cancer have a higher risk
                                 ening.                        slowly and women’s breast        than the average 40-year-
                                 Monday’s update, pub-         tissue becomes less dense        old. Other factors can play
                                 lished in Annals of Inter-    and easier for mammo-            a role, too, including ge-
                                 nal Medicine, is largely a    grams to penetrate, says         netics, breast density and
                                 rewording of guidelines       chief medical officer Dr.        menstrual and pregnancy
                                 originally issued in 2009     Otis Brawley. Between ages       history.
                                 and reconsidered in draft     40 and 44, when breast
                                 form last spring. This time,  cancer is especially un-         PERSONALIZED SCREENING
                                 the task force stresses that  common, the society also         Dueling guidelines mean
                                 “we think thescience  sup-    says women should make           “some people get so
                                                                                                confused they don’t get
                                                                                                screened at all. Some are
                                                                                                too anxious or afraid not
                                                                                                to do more, and it may
                                                                                                not be better for them,”
                                                                                                said breast cancer special-
                                                                                                ist Dr. Laura Esserman of
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