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ACR-1997
            Parameter    EULAR/ACR-2019          SLICC-2012
                                                         82.8%
                                         96.7%
                          96.1%
            Sensitivity
                      (95% CI 95 to 98)
                                         83.7%
                                                         93.4%
                          93.4%      (95% CI 95 to 98)  (95% CI 80 to 85)
            Specificity  (95% CI 91 to 95)  (95% CI 80 to 87)  (95% CI 91 to 95)
                                      Management of Systemic Lupus Erythematosus
            Table 2: Sensitivity and specificity of three classification criteria
                           for SLE in a Malaysian study
            Parameter    EULAR/ACR-2019          SLICC-2012     ACR-1997
                          90.8%          96.1%           82.0%
            Sensitivity  (95% CI 85 to 94)  (95% CI 92 to 98)  (95% CI 75 to 86)
                          94.0%          94.0%           96.0%
            Specificity  (95% CI 87 to 97.5)  (95% CI 86 to 97)  (95% CI 89 to 98)
           Refer to Appendix 3 for 2012 SLICC Classification Criteria for SLE
           and  Appendix 4  for  2019  EULAR/ACR  Classification  Criteria  for
           SLE.
           •  Classification criteria are not diagnostic criteria. It is used to identify a
             relatively homogeneous groups of patients for inclusion in research.


           Recommendation 2
           •  Diagnosis of systemic lupus erythematosus (SLE) should be based
             on clinical manifestations supported by laboratory findings following
             exclusion of alternative diagnoses.
           •  Classification criteria should not be used for the diagnosis of SLE.



































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