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ACR-1997
Parameter EULAR/ACR-2019 SLICC-2012
82.8%
96.7%
96.1%
Sensitivity
(95% CI 95 to 98)
83.7%
93.4%
93.4% (95% CI 95 to 98) (95% CI 80 to 85)
Specificity (95% CI 91 to 95) (95% CI 80 to 87) (95% CI 91 to 95)
Management of Systemic Lupus Erythematosus
Table 2: Sensitivity and specificity of three classification criteria
for SLE in a Malaysian study
Parameter EULAR/ACR-2019 SLICC-2012 ACR-1997
90.8% 96.1% 82.0%
Sensitivity (95% CI 85 to 94) (95% CI 92 to 98) (95% CI 75 to 86)
94.0% 94.0% 96.0%
Specificity (95% CI 87 to 97.5) (95% CI 86 to 97) (95% CI 89 to 98)
Refer to Appendix 3 for 2012 SLICC Classification Criteria for SLE
and Appendix 4 for 2019 EULAR/ACR Classification Criteria for
SLE.
• Classification criteria are not diagnostic criteria. It is used to identify a
relatively homogeneous groups of patients for inclusion in research.

Recommendation 2
• Diagnosis of systemic lupus erythematosus (SLE) should be based
on clinical manifestations supported by laboratory findings following
exclusion of alternative diagnoses.
• Classification criteria should not be used for the diagnosis of SLE.

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