Page 169 - Differential Diagnosis in Small Animal Cytology, The Skin and Subcutis
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VetBooks.ir Differential diagnoses
Soft tissue sarcoma
•
Anaplastic sarcoma of giant cells
•
• Synovial sarcoma (for articular histiocytic sarcoma)
• Osteosarcoma
Pearls and Pitfalls
Cytology is often diagnostic. However, in less straightforward cases, a definitive diagnosis may
require histopathology and immunohistochemistry. The most specific marker used on forma-
lin-fixed samples is the ionized calcium-binding adaptor molecule 1 (IBA1).
Fig. 9.23. Dog. Histiocytic sarcoma. Neoplastic cells show marked anisokaryosis, binucleation and atypical mitoses.
Wright-Giemsa.
