Page 44 - BSAVA Guide to Pain Management in Small Animal Practice
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4  |  Chronic and osteoarthritic pain



        VetBooks.ir     CASE EXAMPLE 1 CONTINUED   analysis should be considered in consultation

                                                   with the dog’s owner.
              CLINICAL SIGNS AND SIGNS OF PAIN        Pilot’s owner returns a week later and
                                                   reports that his appetite has improved, but
              Pilot’s owner presents him to you for   that he has been noticeably sti er and slower
              examination.  e is bright, alert and responsive   to move out of his bed in the morning.
              and you  udge his body condition to be 6 9    he improvement in Pilot s appetite is
               La amme, 1997 . Chest auscultation and   encouraging, but presents a dilemma – his
              abdominal palpation are unremarkable.  is   musculoskeletal pain appears to bene t from
              heart sounds and peripheral pulses are   NSAI  treatment; however, this is potentially
              synchronous with a rate of 1   bpm and he is   causing gastrointestinal adverse e ects. In this
              panting continuously.  is mucous membrane   circumstance, reintroducing the original
              colour is pink and capillary re ll time less   NSAID, whilst continuing omeprazole and
              than 1 second.  he range of motion of both   monitoring closely for further gastrointestinal
              hips is reduced and, during extension of his   e ects, would seem reasonable; however, his
              hips, Pilot stops panting.           owner reported that Pilot was doing less well
                 Signs of pain during physical examination   than previously on the original NSAID and
              are rarely overt in trained dogs. Most   therefore switching to an alternative licensed
              commonly pain is inferred from resistance to   NSAI  could also be considered.  o minimi e
              movement of joints and mild changes in   risks associated with concurrent administra-
              behaviour  lip licking, discontinuing panting    tion of NSAIDs, a washout period without
              in response to joint manipulation.   NSAI  treatment of   7 days is currently
                                                   recommended  Epstein et al.,   1  .  here are
                                                   no current methods of predicting response to
              INVESTIGATIONS AND INITIAL TREATMENT  a particular NSAID. In the case of concerns
                                                   over e cacy in a patient, the authors would
              In instances where there is concern about   tend to replace non coxib NSAI s with coxibs,
              treatment-related gastrointestinal adverse   or vice versa. Monitoring response to treat-
              events, consider assessing faecal occult   ment alterations can be challenging.  he
              blood or serum urea creatinine       severity of  A associated signs can wax and
              (disproportionate increase in urea may be   wane over time. Owners are more likely to
              related to gastrointestinal bleeding .   present dogs when they become aware of an
              Precautionary treatment for gastric ulceration   exacerbation of signs; therefore, improve-
              is appropriate, based on history, and the   ments in the condition related to a natural
              authors would discontinue NSAIDs and   waning in signs  regression to the mean  may
              administer omepra ole at 1 mg kg twice   be erroneously attributed to treatment. Client
              daily for 7 1  days   olbert et al.,   11  before   completed questionnaires such as the
              reinstating NSAID treatment. Inappetance    elsinki Chronic Pain Index   ielm B  rkman
              may also be associated with pain; during the   et al.,    9  or Canine Brief Pain Inventory
              period of NSAID withdrawal the authors   (Brown et al.,    7  can be useful to track
              would prescribe a licensed paracetamol-  changes in levels of pain and disability. Quality
              containing product at the datasheet   of life questionnaires, such as that produced
              recommended doses    .  mg kg three   by Newmetrica  www.newmetrica.com , may
              times daily . NSAI   including paracetamol    be used to investigate how the dog’s disease
              datasheets state that their prescription is   is a ecting his experience of life. Collar
              contraindicated in the presence of   mounted accelerometers are increasingly
              gastrointestinal disorders; therefore,   a ordable and may provide ob ective data
              prescribing NSAIDs or paracetamol in such   on the amount and type of activity the
              cases is  o  licence  and a cost bene t   dog engages in.


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