Page 251 - The Toxicology of Fishes
P. 251
Biotransformation in Fishes 231
Salhab, A. S. and Edwards, G. S., Comparative in vitro metabolism of aflatoxicol by liver preparations from
animals and humans, Cancer Res.. 37, 1016, 1977.
Schirmer, K. et al., Transitory metabolic disruption and cytotoxicity elicited by benzo(a)pyrene in two cell
lines from rainbow trout liver, J. Biochem. Mol. Toxicol., 14, 262, 2000.
Schlenk, D., A comparison of endogenous and exogenous substrates of the flavin-containing monooxygenases
in aquatic organisms, Aquat. Toxicol., 26, 157, 1993.
Schlenk, D., The effect of 2-methylisoborneol on cytochrome P450 expression in the channel catfish (Ictalurus
punctatus), Aquaculture 120, 33, 1994.
Schlenk, D., Use of aquatic organisms as models to determine the in vivo contribution of flavin-containing
monooxygenases to xenobiotic transformation, Mol. Mar. Biol. Biotech., 4, 323, 1995.
Schlenk, D., Occurrence of flavin-containing monooxygenases in non-mammalian eukaryotic organisms,
Comp. Biochem. Physiol., 121C, 185, 1998.
Schlenk, D. and Buhler, D. R., Role of flavin-containing monooxygenase in the in vitro biotransformation of
aldicarb in rainbow trout (Oncorhynchus mykiss), Xenobiotica, 21, 1583, 1991.
Schlenk, D. and Buhler, D. R., Immunological characterization of flavin-containing monooxygenases from
the liver of rainbow trout (Oncorhynchus mykiss): sexual- and age-dependent differences and the effect
of trimethylamine on enzyme regulation, Biochim. Biophys. Acta, 1156, 103, 1993.
Schlenk, D. and El-Alfy, A., Expression of branchial flavin-containing monooxygenase is directly correlated
with salinity-induced aldicarb toxicity in the euryhaline fish (Oryzias latipes), Mar. Environ. Res., 46,
103, 1998.
Schlenk, D. and Li-Schlenk, R., Characterization of liver flavin-containing monooxygenase of the smooth
dogfish shark (Squalus acanthias) and partial purification of liver flavin-containing monooxygenase of
the silky shark (Carcharhinus falciformis), Comp. Biochem. Physiol., 109B, 655, 1994.
Schlenk, D. et al., Channel catfish liver monooxygenases: immunological characterization of constitutive
cytochromes P450 and the absence of active flavin-containing monooxygenases, Biochem. Pharmacol.,
45, 217, 1993.
Schlenk, D. et al., Differential expression and activity of flavin-containing monooxygenases in euryhaline and
stenohaline flatfishes, Comp. Biochem. Physiol., 112C, 179, 1995.
Schlenk, D., Peters, L. D., and Livingstone, D. R., Correlation of salinity with flavin-containing monooxyge-
nase activity but not cytochrome P450 activity in the euryhaline fish (Platichthys flesus), Biochem.
Pharmacol., 52, 815, 1996a.
Schlenk, D., Peters, L. D., and Livingstone, D. R., Down-regulation of piscine flavin containing monooxyge-
nase by decreased salinity in euryhaline flounder (Platichthys flesus), Mar. Environ. Res., 42, 339, 1996b.
Schlenk, D., El-Alfy, A., and Buhler, D. R., Downregulation of hepatic flavin-containing monooxygenase activity
by 17β-estradiol in rainbow trout (Oncorhynchus mykiss), Comp. Biochem. Physiol., 118C, 199, 1997.
Schlenk, D. et al., Cloning and sequencing of cytochrome P450 2X1 from channel catfish (Ictalurus punctatus),
Mar. Environ. Res., 54, 391, 2002.
Schlenk, D., Zubcov, N., and Zubcov E., Effects of salinity on the uptake, biotransformation and toxicity of
dietary seleno-L-methionine to rainbow trout, Toxicol. Sci., 75, 309, 2003.
Schlenk, D., Yeung, C., and Rettie, A., Unique stereoselective sulfoxidation of thioethers indicates novel flavin-
containing monooxygenase in liver of rainbow trout, Mar. Environ. Res., 58, 499, 2004.
Schlenk, D., DeBusk, B. C., and Slattery, M., Effects of dietary exposure to Sarcophyton on detoxification
enzyme expression in butterfly fish (Chaetodon sp.) with varied feeding strategies, Comp. Biochem.
Physiol., in press.
Schlezinger, J. J. and Stegeman, J. J., Induction and suppression of cytochrome P450 1A by 3,3′,4,4′,5-
pentachlorobiphenyl and its relationship to oxidative stress in the marine fish scup (Stenotomus chrysops),
Aquat. Toxicol., 52, 101, 2001.
Schoenhard, G. L. et al., Aflatoxicol-induced hepatocellular carcinoma in rainbow trout (Salmo gairdneri) and
the synergistic effects of cyclopropenoid fatty acids, Cancer Res., 41, 1011, 1981.
Schuur, A. G. et al., In vitro inhibition of thyroid hormone sulfation by hydroxylated metabolites of halogenated
aromatic hydrocarbons, Chem. Res. Toxicol., 11, 1075, 1998.
Senatori, O. et al., Monoamine oxidase in teleosts, Biogenic Amines, 17, 199, 2003.
Seubert, J. M. and Kennedy, C. J., Benzo(a)pyrene toxicokinetics in rainbow trout (Oncorhynchus mykiss)
acclimated to different salinities. Arch. Environ. Cont. Toxicol. 38, 342, 2000.