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412  Section O: Anesthesia in the Patient with Cardiac Disease


              INTRODUCTION                                         Cats with severe atrial dilation may be more likely to
                                                                 be on the brink of developing congestive heart failure
              Risk associated with sedation or general anesthesia of   and/or thromboembolic disease, and may pose a higher
              cats with naturally occurring heart disease is understood   risk than the cat with mild heart disease and minimal
              via  clinical  reports  and  objective  experience,  but  not   atrial  dilation.  This  does  not  indicate  that  cats  with
              blinded prospective studies. In general, studies of small   severe  atrial  dilation  cannot  be  anesthetized,  but  it
              animal morbidity and mortality show good correlation   reflects that their heart disease is usually more severe.
              with the American Society of Anesthesiologists (ASA)   The clinician must weigh the importance of the proce-
              physical status classification (Table 27.1) (Broadbelt et   dure with the risk of the anesthesia and recovery. For
              al. 2007, 2008; Dyson et al. 1998; Gaynor et al. 1999). As   example, dental prophylaxis may carry an increased risk
              expected, this correlation suggests that increased sever-  of anesthetic complications in a cat with cardiomyopa-
              ity of the disease increases anesthetic risk. Therefore, a   thy and atrial enlargement, but if the periodontal disease
              cat with cardiac disease that is currently life-threatening   is severe, and both the dental disorder and the cardio-
              (ASA class 4 or 5) is at higher risk of anesthetic compli-  myopathy  are  expected  to  worsen  over  time,  general
              cations than a cat with stable, yet even severe, cardiac   anesthesia and dental work may be optimal at that time.
              disease (ASA class 3), and all efforts should be made to   Cats with cardiac disease have a higher risk for malig-
              convert decompensated/symptomatic patients to stable/  nant  arrhythmias  than  normal  cats. Anesthetic  agents
              asymptomatic patients prior to anesthesia. In particular,   largely impact cardiovascular function in normal cats,
              nonurgent  procedures  on  cats  with  congestive  heart   and the effects are even more pronounced in cats with
              failure should be postponed until medical management   cardiac disease. Selection of the correct agents, support,
              is  started  and  signs  of  heart  failure  have  resolved  or   and monitoring are all critical to a positive outcome. In
              improved. Similarly, if medical management of cardiac   particular, cats with active congestive heart failure, or a
              disease  without  heart  failure  is  indicated  (e.g.,  beta   history of heart failure, require extremely careful man-
              blocker  administration  in  an  asymptomatic  cat  with   agement and intensive monitoring; anesthesia of these
              hypertrophic  cardiomyopathy),  elective  procedures   patients is best conducted by a specialist.
              should be postponed until the patient has been medi-  Cardiac disorders can be functionally classified into
              cated  for  at  least  a  few  days,  and  reevaluated.  Feline   the following categories:
              cardiovascular patients with the highest anesthetic risk
              are those with
                                                                 •  Systolic myocardial failure (e.g., dilated cardiomyopa-
                                                                   thy)
              •  Active congestive heart failure                 •	 Diastolic	dysfunction	(increased	ventricular	wall	stiff-
              •	 Clinically	significant	bradyarrhythmias	such	as	third-  ness	secondary	to	restrictive	cardiomyopathy	(RCM),
                degree	 atrioventricular	 block	 or	 high-grade	 second-  unclassified	 cardiomyopathy	 (UCM),	 concentric
                degree	atrioventricular	block                      hypertrophy;	 ventricular	 thickening	 due	 to	 pressure
              •	 Clinically	significant	tachycardias	such	as	rapid	(>280	  overload,	 such	 as	 with	 systemic	 hypertension,	 or
                beats/minute)	ventricular	tachycardia              hypertrophic	cardiomyopathy	[HCM]);	or	pericardial
              •	 Intracardiac	thrombi                              disease)


      Anesthesia  Table 27.1.  American	Society	of	Anesthesiologists	classification	system



               ASA	Class     Definition                                  Example

               I             A	normal	healthy	patient                    Young	healthy	cat	undergoing	a	spay
               II            A	patient	with	mild	systemic	disease        Cat	with	mild	mitral	regurgitation	without	left
                                                                         atrial	enlargement
               III           A	patient	with	severe	systemic	disease      Cat	in	congestive	heart	failure,	stable	with	medical
                                                                         management
               IV            A	patient	with	severe	systemic	disease	that	is	a	  Cat	with	ventricular	tachycardia
                             constant	threat	to	life
               V             A	moribund	patient	that	is	not	expected	to	survive	  Cat	with	major	abdominal	hemorrhage,	in
                             without	the	operation                       hypovolemic	shock
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