Page 965 - Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition
P. 965

excess/  in  copper:  the  in  of  risk  using  risk  in

                          with  Diseases  copper  molybdenum  toxidrome  toxicity”)  high  to  ratio  increased  poisoning  when  nitrogen  in  sources  increased  toxemia

                          Association  Other  Relative  relative  deficiency  (“copper  due  sheep  molybdenum  plant;  ammonia  (particularly  nonprotein  dietary  ruminants);  pregnancy  of  sheep








                                    chronic      hepatic  head  wandering,  dyspnea  dysfunction,  hepatic  rarely  ill-  loss  of  of  with  sheep:  to  life  clinical  is  than  not  do  PAs  they  but  E.  contains  induce  no  sheep;


                                    or  hepatopathy.  characterized  refusal;  food  irritability;  of evidence  (icterus,  photosensitization,  yawning,  aimless  walking,  recurrent  nerve  of  signs  Pigs:  grazed  in  general  Cattle:  weight  thrive;  to  bouts  evidence  diarrhea  secondary  of  related  are  curse  cause  PAs  productive  common  sheep  in  rather  se;  per  copper  se,  per  disease;  often  copper:molybdenum  can  in  treatment


                          Toxidrome  subacute  Acute,  megalocytic  Horses:  clinically  depression;  ill-thrift;  insufficiency  secondary  repeated  pressing,  compulsive  to secondary  laryngeal  other  and  encephalopathy).  except  seen  animals.  chronic  thrift;  failure  and/or  unpredictable  aggression;  persistent  and tenesmus  photosensitization  directly  deaths  Paterson’s  uncommon;  decreased  most  span;  found  issue  toxicity  copper  toxicity  PA  enhance  accumulation  the modulate  plantagineum  high  a  which  ratio,  toxicity  copper  effective







                                         pasture  the  is  the          risk;  and          the   and         large
                                       fire  of  content  not  pasture  of  combination  of  forages  (monogastric  highly  cattle  and  goats  relatively  compared  breeds  animal
                          Factors   Overgrazing,  and  the  dominance  PA  when  particularly  dominance  in  reduced  the  poultry,  are  as  susceptible,  moderately  susceptible,  and  susceptible;  sheep  British  Merino/British  crosses;  in  susceptibility



                          Risk         drought  increase  plant;  highest  flowering;  palatable;  as  plant  with  availability  alternative  increases  pigs,  horses  animals)  regarded  sheep  least  merino  wethers  resistant  with  and  breed  variability  individual





                          Distribution  Widespread;  invasive;  highly  high introduced;  losses economic  and  sheep  in  significant  cattle;  in infestations  winter temperate,  of  areas  rainfall  NSW,  and  VIC  the  as  well  southwestern  WA,  of  parts  QLD, southern  eastern  the  and  TAS  of  half










                      Livestock     alkaloids;  high  a  has  copper:molybdenum  and  parts  are  plant  the





                      to  Toxins    Pyrrolizidine  often  plant  all  ratio;  of  stages  toxic
                      Hazardous






                      are              alkaloid
                      That          Hepatogenous  toxicosis

                      Plants  Diseases  pyrrolizidine  (PA)



                      Australian         Winter  grows  are  spring;  dies  rosettes  green  leaves  flowers  shaped  a  is  roots




                      Major  and    plantagineum  curse;  Jane)  annual;  rosette;  a  stems  early  in  spring;  late  flowering;  light  to  egg-shaped  long;  cm  purple;  and  long  trumpets;  with  lateral


                      of  Species  Identification  Echium  (Paterson’s  salvation  growing  as  initially  flowering  produced  in  green  30  to  generally  cm  curved  taproot  numerous  present
                      Summary                         seeds  after  have  hairy  up  are  2 3  like  stout





                      63.2   of

                      TABLE  VetBooks.ir  Common  Name  Disease  Paterson’s  curse  poisoning
   960   961   962   963   964   965   966   967   968   969   970