Page 1267 - Small Animal Internal Medicine, 6th Edition

CHAPTER 73 Common Immune-Mediated Diseases 1239

VetBooks.ir myelofibrosis uncommon

BONE MARROW EVALUATION Erythroid hyperplasia, myelofibrosis in some cases Erythroid hyperplasia, myelofibrosis common Erythroid hypoplasia,

THROMBOCYTOPENIA Yes (60%) Rare No

EVIDENCE OF INFLAMMATION ON CBC Severe inflammatory leukogram in most dogs Mild inflammation in 50% of dogs only No

COOMBS TEST (% POSITIVE) 60%-80% 57% Rarely positive
Comparison of Regenerative IMHA, Nonregenerative IMHA, and PRCA in Dogs

RETICULOCYTE COUNT High Low Low

RATE OF DECREASE OF HEMATOCRIT Fast Variable Slow CBC, Complete blood count; IMHA, immune-mediated hemolytic anemia; PRCA, pure red cell aplasia.

TABLE 73.4 Regenerative hemolytic anemia Nonregenerative anemia PRCA