Page 1305 - Small Animal Internal Medicine, 6th Edition

CHAPTER 77 Complications of Cancer Chemotherapy 1277

TAN M M ? N N N M/S N/M N M/S
VetBooks.ir CCNU M/S M N N N N N M M/S M/S

DTIC M/S M/S N N N N/M M/S N N N

VBL M/S N/M N N N N M/S N N N

VCR N/M N/M N N/M N N M/S N N N

L-ASP N/M N N N M/S M/S N N N N

5-FU M N/M N M N N N/M N N N

ARAC M/S N/M N N N N/M N N N N

MTX M/S M/S N N N N N M N N

CISP M M/S N N/M N N N/M M/S N S ACT, Actinomycin D; araC, cytosine arabinoside; BLEO, bleomycin; CARBO, carboplatin; CCNU, lomustine; CISP, cisplatin; CTX, cyclophosphamide; DOX, doxorubicin; DTIC, dacarbazine; 5-FU, 5-fluorouracil; LEUK, chlorambucil; L-asp, L-asparaginase; M, mild to moderate; MTX, methotrexate; N, none; NA, not applicable; S, severe; TAN, Tanovea; VCR, vincristine; VBL,

CARBO N/M N/M N N N N N N/M N N

LEUK N/M N/M N N N N NA N N N

CTX M/S M N/? N N N/M N M/S N N

Toxicity of Anticancer Agents in Cats and Dogs
ACT M M N N N N M/S N N N

BLEO N N N N N N N N N Y

DOX S M/S M/S N M/S M S M/S N N

TABLE 77.1 Perivascular sloughing vinblastine; ?, questionable.

TOXICITY Myelosuppression Vomiting/diarrhea Cardiotoxicity Neurotoxicity Hypersensitivity Pancreatitis Urotoxicity Hepatotoxicity Pulmonary toxicity