Page 1450 - Small Animal Internal Medicine, 6th Edition

1422 PART XIII Hematology

monoclonal gammopathies are uncommon and occur in Burkhard MJ, et al. Monoclonal gammopathy in a dog with chronic
pyoderma. J Vet Intern Med. 1995;9:357.
association with plasma cell tumors or lymphoma, but they Cerón JJ, et al. Electrophoresis and acute phase protein measure-
VetBooks.ir can rarely occur in cats with FIP (Taylor et al., 2010; Qurollo ment. In: Weiss DJ, Wardrop KJ, eds. Schalm’s veterinary hematol-
et al., 2014).
ogy. 6th ed. Ames, Iowa: Wiley-Blackwell; 2010:1157.
Occasionally an M component is detected in an otherwise
asymptomatic cat or dog, but additional evaluation fails to Ceroón JJ, et al. Acute phase proteins in dogs and cats: current
knowledge and future perspectives. Vet Clin Pathol. 2008;34:85.
reveal a source for the monoclonal gammopathy. Although Fayos M, et al. Serum protein electrophoresis in retired racing
this likely represents the counterpart of human idiopathic Greyhounds. Vet Clin Pathol. 2005;34:397.
monoclonal gammopathy, the patient should be reevaluated Font A, et al. Monoclonal gammopathy in a dog with visceral leish-
frequently for a clinically emerging malignancy. In cats the maniasis. J Vet Intern Med. 1994;8:233.
source of the M component is usually the spleen, in which a Patel RT, et al. Multiple myeloma in 16 cats: a retrospective study.
neoplastic population of well-differentiated plasma cells is Vet Clin Pathol. 2005;34:341.
frequently identified in asymptomatic cats with a monoclo- Qurollo BA, et al. Co-infection with Anaplasma platys, Bartonella
nal gammopathy. Therefore these cats likely have atypical henselae, Bartonella koehlerae and “Candidatus Mycoplasma
myeloma. haemominutum” in a cat diagnosed with splenic plasmacyto-
The treatment of dogs and cats with monoclonal or poly- sis and multiple myeloma. J Feline Med Surg. 2014;16(8):713–
720.
clonal gammopathies is aimed at the primary disease. Refer Tabar MD, et al. Gammopathy in a Spanish dog infected with Bar-
to specific sections throughout this text for discussion of tonella henselae. J Small Anim Pract. 2011;52(4):209–212.
these treatments. Taylor SS, et al. Serum protein electrophoresis in 155 cats. J Feline
Med Surg. 2010;12(8):643–653.
Suggested Readings
Weiser MG, et al. Granular lymphocytosis and hyperproteinemia
Breitschwerdt EB, et al. Monoclonal gammopathy associated with in dogs with chronic ehrlichiosis. J Am Anim Hosp Assoc.
naturally occurring canine ehrlichiosis. J Vet Intern Med. 1987;1:2. 1991;27:84.