Page 606 - Veterinary Immunology, 10th Edition
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Transforming Growth Factor-β, 215
VetBooks.ir Regulation by the Innate Immune System, 216
Th17 Cells, 216
Interleukin-17, 216
Regulatory Macrophages, 218
Indoleamine 2,3-Dioxygenase and
Tolerance, 218
Tolerogenic Dendritic Cells, 218
Regulatory B Cells, 218
Natural Suppressor Cells, 218
When Do Regulatory Cells Work?, 218
Regulation of Apoptosis, 218
Neural Regulation of Immunity, 219
Stress, 219
Autonomic Nervous System, 220
Hypothalamic-Pituitary-Adrenal Cortical
Axis, 220
Neuropeptides and Lymphocytes, 220
LEARNING OBJECTIVES
After reading this chapter, you should be able to:
• Explain how and why T cells do not respond to normal body components.
• Define negative selection, positive selection, clonal anergy, and immunological
tolerance and differentiate between central and peripheral tolerance.
• Understand why B cells are much harder to tolerize than T cells.
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