Page 782 - Veterinary Immunology, 10th Edition

VetBooks.ir Modern Vaccine Technology

Although both killed and modified live vaccines have been
successful in controlling many infectious diseases, there is always a

need to make them more effective, cheaper, and safer (Fig. 24.4).
The use of modern molecular techniques can produce new and
improved vaccines. These vaccines can be divided into several
categories (Table 24.2).

FIG. 24.4 A schematic diagram showing some of the different
ways in which a virus and its antigens may be treated in order to
produce a vaccine.

TABLE 24.2
USDA Classification of Genetically Engineered Veterinary
Biologics

Category Description
I Vaccines that contain inactivated recombinant organisms or purified antigens derived from recombinant
organisms
II Vaccines containing live organisms that contain gene deletions or heterologous marker genes

782