Page 915 - Veterinary Immunology, 10th Edition

VetBooks.ir responses, selectively suppressing these to permit parasite survival,
Ideally, a successful parasite will influence its host's immune

while at the same time allowing other responses to proceed and

thus minimizing immunosuppression. In addition, many parasites
use their host's metabolic or control pathways for their own
purposes. For example, epithelial growth factor and IFN-γ enhance
the growth of Trypanosoma brucei, whereas IL-2 and GM-CSF
promote the growth of Leishmania amazonensis. This sharing of

cytokines by host and parasites reflects the long history of their
association and their success in adapting to a parasitic lifestyle.

915