Page 324 - Problem-Based Feline Medicine
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316  PART 6   CAT WITH WEIGHT LOSS OR CHRONIC ILLNESS


          C. parvum can be difficult to treat, but tylosin (10–15  Clinical signs
          mg/kg q 12 hours PO for 28 days, but may need higher
                                                        Disease can be seen in any age, sex or breed of cat, but
          doses), paromycin (125–165 mg/kg q 12 hours PO for
                                                        is seen  most commonly in kittens from poor envi-
          5 days), or azithromycin (7–15 mg/kg q 12 hours PO
                                                        ronments.
          for 5–7 days) may be effective.
                                                        It may also be seen in pregnant or lactating queens,
          Giardia spp. may be treated with fenbendazole (10–30
                                                        or in cats that have recently changed environments:
          mg/kg/day PO for 5 days) or  metronidazole (10–25
                                                        e.g. changed from having a sedentary life in a warm
          mg/kg q 12–24 hours PO for 5–7 days). Repeated treat-
                                                        environment, to having an active life in adverse weather
          ment may be needed. The possibility of vaccination is
                                                        conditions.
          currently being studied.
                                                        Affected cats show a generalized loss of body condi-
          T. foetus may be treated with ronidazole (10–30 mg/kg
                                                        tion despite a good appetite.
          q 12 hours PO for 14 days).
                                                        They are usually bright and active until terminal stages
          Prognosis                                     of malnutrition.
                                                        There are few specific findings, but severe cases may
          If given the correct treatment, the prognosis for full
                                                        show lethargy, muscle weakness, depression, diarrhea,
          recovery is usually very good.
                                                        neurological signs, blindness and/or ascites.
          Severe infections can occasionally result in permanent
          intestinal damage and chronic clinical signs.  Diagnosis
          Resistant  C. parvum,  Giardia spp. and/or  T. foetus  Diagnosis is based on resolution of clinical signs fol-
          infections can occasionally result in chronic disease.  lowing correction of diet. If necessary, rule out other
                                                        likely differentials.
          Prevention
                                                        Differential diagnosis
          Severe infections can usually be prevented by having a
                                                        These include most other causes of weight loss with a
          good preventative worming policy, giving prompt and
                                                        good appetite. However, given the lack of other clinical
          effective treatment to any animals found to be infected
                                                        signs, the most likely differentials include  intestinal
          or carrying these organisms, improving sanitation, and
                                                        parasites and  some of the malassimilation syn-
          reducing stocking densities.
                                                        dromes including IBD, exocrine pancreatic insuffi-
                                                        ciency, early alimentary lymphosarcoma.
          INADEQUATE NUTRITION**
                                                        Treatment
           Classical signs
                                                        Changing the diet to a suitable well-balanced diet is
           ● Seen in any age, sex or breed of cat, but  usually all the treatment that is necessary. Very severe
             mostly typically in kittens from poor      cases may need supportive care and nursing.
             environments.
           ● Weight loss, often in association with a   Prognosis
             voracious appetite.
                                                        Provided that the malnutrition was not too severe or
           ● Few other signs until terminal stages of
                                                        prolonged, the prognosis for recovery is very good.
             malnutrition.
                                                        Prevention
          Pathogenesis                                  Cats should always be fed appropriate amounts of a
                                                        suitable well-balanced diet that has been designed to be
          Disease due to inadequate nutrition is caused by feed-
                                                        fed to cats.
          ing an inadequate or inappropriate diet.
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