Page 53 - Problem-Based Feline Medicine
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4 – THE CAT WITH STRIDOR OR STERTOR  45


           pression caused by an  extraluminal mass. It has  Weight loss and avoidance of neck collars can be very
           been reported associated with proximal tracheal  beneficial in affected cats.
           obstructions from a trachael granuloma or polyp.
           The cough is often harsh, non-productive and parox-  LARYNGEAL EOSINOPHILIC GRANULOMA
           ysmal, ending in a gagging episode which may appear
           to be productive.                               Classical signs

           Cervical trachea collapse produces inspiratory dysp-  ● Stridor from laryngeal region.
           nea, while intrathoracic tracheal or bronchial collapse  ● Swollen, edematous arytenoid cartilages
           will lead to mostly expiratory dyspnea. Stridor is  of larynx.
           occasionally reported.

                                                          Clinical signs
           Diagnosis
                                                          Syndrome often occurs weeks or months after signs of
           Radiographs may show attenuation of the tracheal or
                                                          viral upper respiratory tract infection.
           bronchial lumina. Fluoroscopy may be more sensitive
           for dynamic collapse.                          Stridor from laryngeal region is evident.
           Tracheobronchoscopy is valuable in both diagnosing  The larynx appears edematous and swollen.
           and grading the severity of the collapse.
                                                          With stress, cats become dyspneic and may mouth
                                                          breathe.
           Differential diagnosis

           Tracheitis from feline rhinotracheitis virus is generally  Diagnosis
           associated with other upper respiratory signs.
                                                          Visual appearance and biopsy are diagnostic.
           Laryngeal paralysis or edema, tracheal foreign body  Biopsy reveals an eosinophilic granuloma.
           and tracheobronchial neoplasm can be differentiated
           endoscopically.
                                                          Differential diagnosis
           Small airway disease (feline asthma/bronchitis com-
                                                          Invasive squamous cell carcinoma may have a similar
           plex) can worsen upper airway collapse, but generally
                                                          appearance but can be differentiated on biopsy.
           diagnosis is based on the radiographic peribronchiolar
           pattern and airway inflammation on lung wash cytology.  Other inflammatory infiltrations of the larynx, for
                                                          example with lymphocyte, may appear similar, but are
           Treatment                                      differentiated on biopsy.

           Medical treatment is indicated for a short and mini-
           mally attenuated collapsing segment, and consists pri-  Treatment
           marily of antitussive therapy (butorphanol 1 mg/cat PO
                                                          Oral steroids such as prednisolone 2 mg/kg bid PO for
           q 6–12 h as needed).
                                                          10 days, then taper dose.
           Surgical therapy may be indicated with severe col-
                                                          If oral medication cannot be given, methylprednisolone
           lapse due to trauma. This generally requires referral to
                                                          acetate (2–4 mg/kg 7 days for 2–6 treatments), can be
           a specialist with experience in airway surgery.
                                                          used.
           Extraluminal spiral ring prostheses made from a 3 ml
           syringe case were successful in reducing signs in two  Occasionally, refractory cases need chlorambucil
           cats.                                          (0.1–0.2 mg/kg q 24 h initially PO, IM, then q 48 h).
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