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58   PART 2   CAT WITH LOWER RESPIRATORY TRACT OR CARDIAC SIGNS


          Intermittent vomiting and inappetence are the most  Typically, there is acute onset of single limb paresis
          common gastrointestinal signs.                or paralysis, which most often involves the hindlimbs.
                                                        Signs may be bilateral with a “saddle thrombus” at the
          Diagnosis                                     aortic trifurcation.

          Thoracic radiographs demonstrate bowel loops, or  On physical examination the limb is cool and pulse-
          space-occupying soft tissue densities within the pleural  less, with cyanotic foot pads or nail beds. The gas-
          or pericardial space. Globose cardiomegaly is evident  trocnemius muscle is firm and painful on palpation.
          with peritoneopericardial diaphragmatic hernia.
                                                        Signs of congestive heart failure including cyanosis,
          Other imaging modalities such as ultrasonography, pos-  respiratory distress, or evidence of pleural effusion may
          itive contrast upper GI series, pneumoperitoneography  be present. Dyspnea and tachypnea may be acutely
          or contrast injected into the abdomen (celiogram) may  exacerbated. Heart murmurs, arrhythmias and gallops
          be useful for diagnosis.                      are often evident.

          Differential diagnosis                        Diagnosis
          Pleural space disease (effusions, pneumothorax, mass  Diagnosis is based on the clinical signs and confirmed
          lesions), pericardial effusion and cardiomyopathy may  by evidence of lack of blood flow in the distal limb
          have similar signalment and signs to traumatic  measured by a Doppler flow meter.
          diaphragmatic hernia, but can usually be differentiated
                                                        Thoracic radiography and ultrasonography
          on radiography and ultrasonography.
                                                        demonstrate underlying heart disease, often with sig-
                                                        nificant chamber enlargement, especially of the left
          Treatment                                     atrium.
          Treatment consists of surgical repair after stabilizing  Contrast arteriography of the affected limb is the
          the patient. If dyspnea is the major clinical sign, stabi-  “gold standard”, but not frequently used in clinical
          lization may not be possible until the pericardial or  cases.
          pleural cavities are evacuated. Oxygen therapy is of lit-
          tle value in a patient with severe pleural occupation.
                                                        PULMONARY THROMBOEMBOLISM*

          AORTIC THROMBOEMBOLISM*                        Classical signs
                                                         ● Sudden onset of severe dyspnea with
           Classical signs
                                                           normal lung parenchyma radiographically.
           ● Acute single or bilateral limb paresis or   ● Peracute dyspnea, orthopnea, tachypnea.
             paralysis, most often involving hindlimbs.  ● Cyanosis, collapse.
           ● Signs of congestive heart failure –         ● Cough, with or without hemoptysis.
             cyanosis, respiratory distress, pleural
             effusion.
           ● Heart murmurs, arrhythmias and gallops.    Pathogenesis
                                                        Pulmonary thromboembolism involves  embolic
          See main reference on page 915 for details (The Weak  showering of the pulmonary arterial tree, causing
          and Ataxic Cat or Paralyzed Cat).             obstruction of blood flow to that portion of the lung.

          Clinical signs                                Thrombi may be produced locally (i.e., feline heart-
                                                        worm disease), or may embolize from distant locations.
          Cardiomyopathy in cats is sometimes associated with  Thrombi may originate in the right atrium (cardiomy-
          thrombus formation in the left atrium. The thrombus may  opathy, advanced tricuspid valvular disease), caudal
          be dislodged, and most commonly obstructs the aorta at  vena cava, femoral veins, mesenteric venous system or
          its trifurcation (saddle thrombus).           jugular veins.
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