Page 208 - Rule Outs in Small Animal Medicine, Problem-oriented Assessment of Problems in Physical Examination and Clinical Pathology, 2nd Edition
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                                  Internal Medicine                          Internal Medicine
                                  General health problems                   General health problems

                                                       Internal Medicine
                                                  Internal Medicine

                                                     General health problems  General health problems

                                                  Increased body

                                                  temperature
  VetBooks.ir  Internal Medicine        Oedema  Influence of exogenous   Fever  Influence of   Prehepatic  Icterus  Increased heat   Hyperthermia  Decreased heat   General health problems   VET
            General health problems
                                                                                             Internal Medicine

            Rubrik

                                                 Local
                                                             Increased
                                     pyrogens   endogenous pyrogens  Lymph drainage   degradation of   production  – Increased  dissipation  Hepatic

                                                         disorders
                                   – Doxycycline therapy  Tissue   Autoimmune  Vascular permeability   haemproteins
                                                                        Increased
                                   (cat)  resorption  disease  Neoplasia  disorders  Infection  Muscle activity  metabolism  environmental
                                                                            temperature
                   Generalised            Increased local                   – Insufficient  air   Posthepatic
                                          hydrostatic pressure  Haemoglobin   Hepatic dysfunction
                                                                            circulation (e.g. car,
                                                         â Lymphadenopathy  Myoglobin   Disturbance of
                                                        degradation         narrow cage)
                                                                                  hepatocellular
                        Increased hydrostatic        Vasculitis  p. 10  degradation  – Seizures  – Hyperthyroidism  bilirubin transport  Bile duct rupture
                                                                 (e.g. status epilepticus)
                    Decreased oncotic   pressure  – Thrombus  Local inflammation  – Sport (e.g. dog racing)  – Liver fibrosis  Bile duct obstruction
               Generalised   pressure                 Haemolysis  Haemorrhage in   – Muscle spasms   – Liver cirrhosis
                vasculitis                                body cavities or   Massive destruction of  – Malignant hyperthermia   – Hepatic lipidosis  Lack of glucose   Disturbance of
                                                                 (e.g. tetanus)
                                                                           – Liver neoplasia
                                                          haematoma
                         – Cardiac failure     – Insect bite/sting Extravascular   – Leishmaniosis     muscle cells (rare in  (only horse and cow)  transport system  – Cholangiohepatitis
                                                                                    the bilirubin
                                                    – Dirofilariosis
                                                               small animals)
                                               – Thrombophlebitis
                                                                                           – Bile duct
                                                                                    (by high TNF-α)
               – Leishmaniosis  â Hypoalbuminaemia  haemolysis  Intravascular             – Pancreatitis
                                                                                           carcinoma
               – Dirofilariosis  p. 154                  haemolysis  – Trauma             – Gall bladder
                                                              – Myositis
                                                                                   – Severe
                                                                                           stones
                                                                                   systemic
                                               – Immune-mediated haemolytic
                                                anaemia                            inflammation
                                               – Babesiosis  – Copper intoxication  (e.g. sepsis, FIP)

                                                      – Tap water enema (cat)
                                               – Haemoplasma infection
                                                      – Hypophosphataemia (e.g. during therapy
                                                      of diabetic ketoacidosis)
                                                      anaemia
                                                      – Severe immune-mediated haemolytic
                                                     – Zinc intoxication
                                                     – Severe babesiosis

                                  4                  – Onion or garlic intoxication  5
                                                     hemangioendothelioma)
                                                     – Destruction (e.g. DIC, caval syndrome,



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           How to achieve a reliable diagnosis –
           even in complex clinical cases!
           Internal medicine cases can be complex and challenging. To manage such challenges,
           it is helpful to know the possible pathophysiological causes of a particular clinical
             problem, to be able to evaluate each problem in an individual case and to exclude
           anything not relevant for this patient using diagnostic pathways. This book  describes                           Rule outs in small animal medicine
           this process of exclusion (“ruling out”) for all aspects of internal medicine in dogs
           and cats, and  ultimately leads to confirmation of a specific diagnosis. Rule outs
             therefore are an  important basis for everyday clinical work and provide a practical
           guideline for a systematic problem-oriented approach to patients.
           For students, these rule outs are a prerequisite for understanding the pathophysio-
           logy of clinical presentations and laboratory changes. For experienced clinicians,
           rule outs are a helpful diagnostic guide especially when dealing with complex cases.
           ESSENTIAL
           Expert knowledge for everyday clinical work
           UNIQUE
           The easy way to a correct diagnosis: comprehensive and concise                                                   Hartmann | Berg | Berg (eds.)
                                                                                             ISBN 978-3-89993-983-5
           VET SCRIPTUM  Helpful tool for studies and exams!
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